Manuscripts

Manuscripts Utilizing VPS Data

VPS is the Only Way to Truly Benchmark Your PICU’s Performance as a
Fundamental Requirement for Quality Improvement

2024

Zinter M, Brazauskas R, Strom J, Chen S, Bo-Subait S, Sharma A, et al. Intensive care risk and long-term outcomes in pediatric allogeneic hematopoietic cell transplant recipients. Blood Adv 2024; 8 (4): 1002–1017. doi: https://doi.org/10.1182/bloodadvances.2023011002

Flaherty B, Smith M, Dziorny A, Srivastava R, Cook L, Keenan H. Probabilistic Linkage Creates a Novel Database to Study Bronchiolitis Care in the PICU. Hosp Pediatrics. 2024 Feb 7:e2023007397. doi: 10.1542/hpeds.2023-007397. Epub ahead of print. PMID: 38321928.

2023

McCluskey, C. K., Black, T. R., Zee-Cheng, J., Klein, M. J., Lin, A., Rogerson, C. M., … & Rotta, A. T. (2023). Suicide and Self-Harm in Adolescents During the COVID-19 Pandemic: A US Virtual Pediatric Systems, LLC, Database Study of PICU Admissions, 2016–2021. Pediatric Critical Care Medicine, 10-1097.

Tjoeng, Y.L., Olsen, J., Friedland-Little, J.M. et al. Association Between Race/Ethnicity and Severity of Illness in Pediatric Cardiomyopathy and Myocarditis. Pediatr Cardiol (2023). https://doi.org/10.1007/s00246-023-03203-z

Mazur, L., Veten, A., Ceneviva, G., Pradhan, S., Zhu, J., Thomas, N. J., & Krawiec, C. (2023). Characteristics and Outcomes of Intrahospital Transfers from Neonatal Intensive Care to Pediatric Intensive Care Units. American Journal of Perinatology.

Wollny K, McNeil D, Moss S, Sajobi T, Parsons S, ; Benzies K, Metcalfe A. Unplanned Extubations Requiring Reintubation in Pediatric Critical Care: An Epidemiological Study. Pediatric Critical Care Medicine 24(4):p 311-321, April 2023. | DOI: 10.1097/PCC.0000000000003167

Holton C, Lee B, Escobar H, Benton T, Bauer P. Admission Pao2 and Mortality Among PICU Patients and Select Diagnostic Subgroups. Pediatric Critical Care Medicine ():10.1097/PCC.0000000000003247, April 24, 2023. | DOI: 10.1097/PCC.0000000000003247

Ettinger, N.A., Guffey, D., Anum, S.J. et al. Multi-center retrospective study of children with sickle cell disease admitted to pediatric intensive care units in the United States. Sci Rep 13, 6758 (2023). https://doi.org/10.1038/s41598-023-32651-z

Pineda, Erika Y. MD, FAAP1; Sallam, Mohammad MD2; Breuer, Ryan K. MD1; Perez, Geovanny F. MD, MSc3; Wrotniak, Brian PhD4; Swayampakula, Anil Kumar MD, MPH1. Asthma Cases Treated With Inhaled Anesthetics or Extracorporeal Membrane Oxygenation: A Virtual Pediatric Systems Database Study of Outcomes. Pediatric Critical Care Medicine ():10.1097/PCC.0000000000003242, April 24, 2023. | DOI: 10.1097/PCC.0000000000003242

Heneghan, J; Goodman, D; Ramgopal, S. Variable Identification of Children With Medical Complexity in United States PICUs. Pediatric Critical Care Medicine 24(1):p 56-61, January 2023. | DOI: 10.1097/PCC.0000000000003112

Ettinger NA, Kiskaddon A, McNeely L, Craycraft J, Rogers A, Achuff BJ, Guffey D, Musick M. Retrospective observational study of chloral hydrate use in mechanically-ventilated pediatric intensive care unit (PICU) patients 2012-2017. Front Pharmacol. 2023 May 4;14:1111528. doi: 10.3389/fphar.2023.1111528. PMID: 37214459; PMCID: PMC10192606.

Lenz, K. B., Nishisaki, A., Lindell, R. B., Yehya, N., Laverriere, E. K., Bruins, B. B., … & Fitzgerald, J. C. (2023). Peri-Intubation Adverse Events in the Critically Ill Child After Hematopoietic Cell Transplant. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 26 Apr 2023

2022

Lindell RB, Fitzgerald JC, Rowan CM, Flori HR, Di Nardo M, Napolitano N, Traynor DM, Lenz KB, Emeriaud G, Jeyapalan A, Nishisaki A.  For the National Emergency Airway Registry for Children (NEAR4KIDS) and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. The Use and Duration of Preintubation Respiratory Support Is Associated With Increased Mortality in Immunocompromised Children With Acute Respiratory Failure*. Critical Care Medicine: 2022 Jul;50(7):1127-37. doi: 10.1097/CCM.0000000000005535.

Mount MC, Ji X, Kattan MW, Slain KN, Clayton JA, Rotta AT, Shein SL. Derivation and Validation of the Critical Bronchiolitis Score for the PICU. Pediatric Critical Care Medicine. 2022 Jan;23(1):p e45-e54. doi: 10.1097/PCC.0000000000002808.

McCluskey CK, Klein MJ, Steward SC, Rotta AT. Suicide and Self-Harm in Children and Adolescents Admitted to PICUs in the United States. Pediatric Critical Care Medicine. 2022 Jan;23(1):e66-e70.doi: 10.1097/PCC.0000000000002836.

Steif J, Brant R, Sreepada RS, West N, Murthy S, Görges, M. Prediction Model Performance with Different Imputation Strategies: A Simulation Study Using a North American ICU Registry. Pediatric Critical Care Medicine. 2022 Jan;23(1): e29-e44. doi: 10.1097/PCC.0000000000002835.

Bhat MA, Soto-Campos G, Scanlon MC. Relationship Between Pediatric Intensive Care Unit Length of Stay and 24-h Unplanned Readmission Rate. Health Serv Res. 2022 Jun;57(3):598-602. doi: 10.1111/1475-6773.13952. Epub 2022 Feb 24. PMID: 35149985; PMCID: PMC9108078.

Smith MA, Dinh D, Ly NP, Ward SL, McGarry ME, Zinter MS. Changes in the Use of Invasive and Noninvasive Mechanical Ventilation in Pediatric Asthma: 2009-2019. Ann Am Thorac Soc. 2023 Feb;20(2):245-253. doi: 10.1513/AnnalsATS.202205-461OC. PMID: 36315585; PMCID: PMC9989865.

DeSanti RL, Balakrishnan B, Rice TB, Pineda JA, Ferrazzano PA. The Utilization of Critical Care Resources in Pediatric Neurocritical Care Patients. Pediatr Crit Care Med. 2022 Sep 1;23(9):676-86. doi: 10.1097/PCC.0000000000002992. Epub 2022 May 27. PMID: 35667123.

Aures R, Rosenthal J, Chandler A, Raybould T, Flaherty M. Outcomes of Pediatric Drowning in the Pediatric Intensive Care Unit. Journal of Pediatric Intensive Care. 2022 Jul 28; doi : 10.1055/s-0042-1751267.

Lew A, Morrison JM, K Amankwah E, Sochet AA. Heliox Prescribing Trends for Pediatric Critical Asthma. Respir Care. 2022 May;67(5):510-9. doi: 10.4187/respcare.09385. PMID: 35473851.

McCluskey CK, Zee-Cheng JE, Klein MJ, Scanlon MC, Rotta AT, Remy KE, Carroll CL, Shein SL. The Temporal Relationship Between Local School Closure and Increased Incidence of Pediatric Diabetic Ketoacidosis. Frontiers in Pediatrics. 2022 Mar 11;10:812265. doi: 10.3389/fped.2022.812265. PMID: 35359897; PMCID: PMC8963207.

Raina R, Mawby I, Chakraborty R, Sethi SK, Mathur K, Mahesh S, Forbes M. Acute Kidney Injury in COVID-19 Pediatric Patients in North America: Analysis of the Virtual Pediatric Systems Data. PLoS One. 2022 Apr 26;17(4):e0266737. doi: 10.1371/journal.pone.0266737. PMID: 35472149; PMCID: PMC9041802.

Lindell RB, Fitzgerald JC, Rowan CM, Flori HR, Di Nardo M, Napolitano N, Traynor DM, Lenz KB, Emeriaud G, Jeyapalan A, Nishisaki A. National Emergency Airway Registry for Children (NEAR4KIDS) and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network The Use and Duration of Preintubation Respiratory Support Is Associated With Increased Mortality in Immunocompromised Children With Acute Respiratory Failure. Critical Care Medicine. 2022 Jul 1;50(7):1127-1137. doi: 10.1097/CCM.0000000000005535. Epub 2022 Mar 14. PMID: 35275593.

Logan G, Miller K, Kohler M, Loi M, Maddux A. Outcomes of Critically Ill Children With Acute Lymphoblastic Leukemia and Cytokine Release Syndrome Due to Chimeric Antigen Receptor T Cell Therapy: US, Multicenter PICU, Cohort Database Study. Pediatric Critical Care Medicine.2022 Oct 4; doi: 10.1097/PCC.0000000000003079. Epub ahead of print. PMID: 36194016.

Snooks K, Scanlon MC, Remy KE, Shein SL, Klein MJ, Zee-Cheng J, Rogerson CM, Rotta AT, Lin A, McCluskey CK, Carroll CL. Characteristics and Outcomes of Critically Ill Children With Multisystem Inflammatory Syndrome. Pediatr Crit Care Med. 2022 Aug 22. doi: 10.1097/PCC.0000000000003054. Epub ahead of print. PMID: 35994614.

Godsey C, Gabor R, Oelstrom M, Hagen S, Peterson J, Taylor J, Mikhailov T. Changes in Pediatric Intensive Care Admissions in Wisconsin During the 2020 COVID-19 Pandemic. WMJ.  2022 Oct;121(3):194-200. PMID: 36301645.

Becker AE, Teixeira SR, Lunig NA, Mondal A, Fitzgerald JC, Topjian AA, Weiss SL, Griffis H, Schramm SE, Traynor DM, Vossough A, Kirschen MP. Sepsis-Related Brain MRI Abnormalities Are Associated With Mortality and Poor Neurological Outcome in Pediatric Sepsis. Pediatric Neurology. 2022 Mar;128:1-8. ISSN 0887-8994, doi: https://doi.org/10.1016/j.pediatrneurol.2021.12.001.

Vo M, Miller K, Bennett TD, Mourani PM, LaVelle J, Carpenter TC, Scott Watson R, Pyle LL, Maddux AB. Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness. Pediatr Pulmonol. 2022 Apr 19;57(7):1651-9. doi: 10.1002/ppul.25934. Epub ahead of print. PMID: 35438830; PMCID: PMC9233134

McCrory MC, Woodruff AG, Saha AK, Evans JK, Halvorson EE, Bass AL. Nonadherence to appropriate tidal volume and PEEP in children with pARDS at a single center. Pediatr Pulmonol. 2022 Jul 1. doi: 10.1002/ppul.26060. Epub ahead of print. PMID: 35778788.

Kirschen MP, Topjian A. Who Falls Under the Pediatric Neurocritical Care Umbrella? Pediatr Crit Care Med. 2022 Sep 1;23(9):747-9. doi: 10.1097/PCC.0000000000003015. Epub 2022 Aug 29. PMID: 36053034.

Zinter MS, et al. Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network’s Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. Pediatric Critical Care Medicine. 2022;23(3): 205-13.

Epstein R, Ohliger SJ, Cheifetz IM, Malay S, Shein SL. Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients and Its Correlation With Changes in Clinical Outcomes: A Virtual PICU Database Study. Pediatr Crit Care Med. 2022 Jul 1;23(7):544-554. doi: 10.1097/PCC.0000000000002950. Epub 2022 Apr 18. PMID: 35435884.

2021

Nikolla DA, Ata A, Brundage N, Carlson JN, Frisch A, Wang HE, Markovitz B. Change in Frequency of Invasive and Noninvasive Respiratory Support in Critically Ill Pediatric Subjects. Respiratory Care. 2021 Aug;66(8):1247-53. doi: 10.4187/respcare.08712. Epub 2021 May 4. PMID: 33947789.

Johnson KT, Görges M, Murthy S. Characteristics and Timing of Mortality in Children Dying With Infections in North American PICUs. Pediatric Critical Care Medicine. 2021 Feb 12;1(1):doi: 10.1097/PCC.0000000000002667.

Badruddin S, Clayton J, McKee B, Slain K, Rotta A, Malay S, Shein S. Prevalence of Reintubation Within 24 Hours of Extubation in Bronchiolitis: Retrospective Cohort Study Using the Virtual Pediatric Systems Database. Pediatric Critical Care Medicine. 2021;22(5): 474-82. doi: 10.1097/PCC.0000000000002581.

Ehinger JK, Karlsson M, Sjövall F, Leffler M, McCormack SE, Kubis SE, Åkesson A, Falk MJ, Kilbaugh TJ. Predictors of Outcome in Children with Disorders of Mitochondrial Metabolism in the Pediatric Intensive Care Unit. Pediatr Res. 2021 Dec;90(6):1221-7. doi: 10.1038/s41390-021-01410-z. Epub 2021 Feb 24. PMID: 33627817; PMCID: PMC7903037.

Thompson NE, Wakeham MK. Is Early Extubation Associated with Better Outcome After Neonatal Congenital Heart Disease Surgery? J Pediatr Intensive Care. 2021;1(10). Epub ahead of print. doi: 10.1055/s-0041-1726092.

Edwards JD, Jia H, Baird JD. The Impact of Eligibility for Primary Attendings and Nurses on PICU Length of Stay. J Crit Care. 2021 Apr;62:145-50. doi: https://doi.org/10.1016/j.jcrc.2020.12.006. PMID: 33383307

Spaulding AB, Zagel AL, Cutler GJ, Brown A, Zier JL. Organ Donation Authorization After Brain Death Among Patients Admitted to PICUs in the United States, 2009-2018. Pediatric Critical Care Medicine. 2021 Mar 1;22(3):303-311. doi: 10.1097/PCC.0000000000002648. PMID: 33332867.

McCrory M,  Woodruff A, Saha A, Halvorson E, Critcher B, Holmes J. Characteristics of Burn-Injured Children in 117 U.S. PICUs (2009–2017). Pediatric Critical Care Medicine. 2021 Jan 20;22(7):616-28.doi: 10.1097/PCC.0000000000002660.

Bagdure D, Foster CB, Garber N, Holloway A, Day J, Lee J, Soto-Campos G, Brundage N, Bhutta A, Graciano AL. Outcomes of Children With Firearm Injuries Admitted to the PICU in the United States. Pediatric Critical Care Medicine. 2021 Nov;22(11):944-9. doi: 10.1097/PCC.0000000000002785.

Ross PA, Engorn BM, Newth CJL, Gordon C, Soto-Campos G, Bhalla AK. Declining Procedures in Pediatric Critical Care Medicine Using a National Database. Critical Care Explorstions. 2021 Mar 5;3(3):e0359. doi: 10.1097/CCE.0000000000000359. PMID: 33786435; PMCID: PMC7994033.

Morgan RW, Himebauch AS, Griffis H, Quarshie WO, Yeung T, Kilbaugh TJ, Topjian AA, Traynor D, Nadkarni VM, Berg RA, Nishisaki A, Sutton RM. Pulmonary Hypertension Among Children with In-hospital Cardiac Arrest: A Multicenter Study. Resuscitation. 2021 Sep 16;168:52-7. doi: 10.1016/j.resuscitation.2021.09.009. Epub ahead of print. PMID: 34536558.

Schlueter D, Kovaleski C, Walter V, Thomas NJ, Krawiec C. Impact of Body Mass Index and Initial Respiratory Support on Pediatric Subjects in Acute Respiratory Failure. Respiratory Care. 2021 Apr 20;67(11). doi: 10.4187/respcare.08735. Epub ahead of print. PMID: 33879564.

Moffitt CA, Deakins K, Cheifetz I, Clayton JA, Slain KN, Shein SL. Use of Negative Pressure Ventilation in Pediatric Critical Care: Experience in 56 PICUs in the Virtual Pediatric Systems Database (2009-2019). Pediatric Critical Care Medicine. 2021 Jun 1;22(6):e363-8. doi: 10.1097/PCC.0000000000002690. PMID: 33729731.

Lew A, Morrison JM, Amankwah EK, Elliott RA, Sochet AA. Volatile Anesthetic Agents for Life-threatening Pediatric Asthma: A Multicenter Retrospective Cohort Study and Narrative Review. Pediatric Anaesthasia. 2021 Sep 12;31:1340–9. doi:  https://doi.org/10.1111/pan.14295.

Hafzalah M, Wang Y, Tripathi S. Meaningful Use of Inhaled Nitric Oxide (iNO): a Cross-Sectional National Survey. SN Comprehensive Clinical Medicine. 2021;3:945-8. doi: https://doi.org/10.1007/s42399-021-00818-2.

Tripathi S, Kim M. Outcome Differences Between Direct Admissions to the PICU From ED and Escalations From Floor. Hospital Pediatrics. 2021 Nov;11(11): e1237-45, epublish ahead of print 2021 Oct 8. doi: https://doi.org/10.1542/hpeds.2020-005769.

Zee-Cheng J, McCluskey C, Klein M, Pineda J, Remy K, Carroll C. Changes in Pediatric ICU Utilization and Clinical Trends During the Coronavirus Pandemic. CHEST. 2021 Aug 1;160(2):529-37. Published:2021 Mar 12;160(2):529-37 doi: https://doi.org/10.1016/j.chest.2021.03.004.

Rogerson CM, Lin A, Klein MJ, Zee-Cheng J, McCluskey CK, Scanlon MC, Rotta AT, Remy KE, Shein SL, Carroll CL. School closures in the United States and severe respiratory illnesses in children: A normalized nationwide sample. Pediatr Crit Care Med. 2021 Apr 21; doi: 10.1097/pcc.0000000000002967. PMID: 35447632.

Zee-Cheng J, McCluskey CK, Klein MJ, Scanlon MC, Rotta AT, Shein SL, Pineda JA, Remy KE, Carroll CL. Changes in Pediatric Intensive Care Unit Utilization and Clinical Trends during the Coronavirus Pandemic. J CHEST. 2021 Mar 4; doi: https://doi.org/10.1016/j.chest.2021.03.004.

Baloglu O, Nagy M, Ezetendu C, Latifi SQ, Nazha A. Simplified Pediatric Index of Mortality 3 Score by Explainable Machine Learning Algorithm, Critical Care Explorations: 2021 Oct;3(10):e0561. doi: 10.1097/CCE.0000000000000561.

Zee-Cheng J, McCluskey CK, Klein MJ, Scanlon MC, Rotta AT, Shein SL, Pineda JA, Remy KE, Carroll CL. Changes in Pediatric Intensive Care Unit Utilization and Clinical Trends During the Coronavirus Pandemic. CHEST. 2021;160(2):529-37. doi: 10.1016/j.chest.2021.03.004. Epub 2021 Mar 13. PMID: 33727033; PMCID: PMC7954775.

Ginsburg S, Conlon T, Himebauch A, Glau C, Weiss S, Weber M, O’Connor M, Nishisaki A. Left Ventricular Diastolic Dysfunction in Pediatric Sepsis: Outcomes in a Single-Center Retrospective Cohort Study. PCCM. 2021;(22)3: 275-85. doi: 10.1097/PCC.0000000000002668.

Maddux A, Campbell K, Woodruff A, LaVelle J, Lutmer J, Kennedy C, Malakooti M, McGuire J, Shekerdemian L, Harris Z, McCrory M, Carpenter T. The Impact of Strict Public Health Restrictions on Pediatric Critical Illness. Critical Care Medicine. 2021 Jul 12;doi: 10.1097/CCM.0000000000005200.

Leimanis-Laurens ML, Ferguson K, Wolfrum E, Boville B, Sanfilippo D, Lydic TA, Prokop JW, Rajasekaran S. Pediatric Multi-Organ Dysfunction Syndrome: Analysis by an Untargeted “Shotgun” Lipidomic Approach Reveals Low-Abundance Plasma Phospholipids and Dynamic Recovery over 8-Day Period, a Single-Center Observational Study. Nutrients. 2021 Feb 27;13(3):774. doi: https://doi.org/10.3390/nu13030774.

Epstein R, Shein SL. Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients and its Correlation with Changes in Clinical Outcomes. Journal of American Collage of Cardiology. 2021 May 11;77(18 Suppl 1):477. doi: 10.1016/S0735-1097(21)01846-5.

2020

Bagdure DN, Custer JW, Foster CB, Blackwelder WC, Mishcherkin V, Portenoy A, Bhutta A. The Impact of Dedicated Cardiac Intensive Care Units on Outcomes in Pediatric Cardiac Surgery: A Virtual Pediatric Systems Database Analysis. Journal Pediatric Intensive Care. 2020 Aug 10;epub ahead of print. doi: 10.1055/s-0040-1714718.

Carter MR, Khan AH, Salman T, Speicher R, Rotta AT, Shein SL. Emergency Room Endotracheal Intubation in Children with Bronchiolitis: A Cohort Study Using a Multicenter Database. Health Sci Rep. 2020 Jun 30;3(3):e169. doi: 10.1002/hsr2.169. PMID: 32617417; PMCID: PMC7325424.

Patel N, Petersen TL, Simpson PM, Feng M, Hanson SJ. Rates of Venous Thromboembolism and Central Line-Associated Bloodstream Infections Among Types of Central Venous Access Devices in Critically Ill Children. Critical Care Med. 2020 Jun 24;48(9):1340-8. doi: 10.1097/CCM.0000000000004461 PMID: 32590391.

Badruddin SS, Clayton JA, McKee BP, Slain KN, Rotta AT, Malay S, Shein SL. Prevalence of Reintubation Within 24 Hours of Extubation in Bronchiolitis: Retrospective Cohort Study Using the Virtual Pediatric Systems Database. Pediatr Crit Care Med. 2020 Oct;22(5):474-82. doi: 10.1097/PCC.0000000000002581. PMID: 33031349.

Tjoeng Y, Jenkins K, Deen J, Chan T. Association Between Race/Ethnicity, Illness Severity, and Mortality in Children Undergoing Cardiac Surgery.  The Journal of Thoracic and Cardiovascular Surgery.  2020 Jun 24;160(6):1570-9. doi: https://doi.org/10.1016/j.jtcvs.2020.06.015.

Christian CE, Thompson NE, Wakeham MK. Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs*. Pediatric Critical Care Medicine. 2020 Jul;21(7):620-4. doi: 10.1097/PCC.0000000000002267.

“Mahendra M, McQuillen P,  Adams Dudley R, Steurer M. Variation in Arterial and Central Venous Catheter Use in Pediatric Intensive Care Units.

Journal of Intensive Care Medicine. 2020 Sep 24;1(8): epub ahead of print. doi: https://doi.org/10.1177/0885066620962450.”

Hanson S, Mahajerin A, Petty J, Shabanova V, Faustino V. Risks of Venous Thrombosis and Bleeding in Critically Ill Adolescents After Trauma or Major Surgery.  Journal of Pediatric Surgery.  2020 Jul 25;56(2):302-8. doi: https://doi.org/10.1016/j.jpedsurg.2020.06.037.

Smith MA, McGarry ME, Ly NP, Zinter MS. Outcomes of Children With Cystic Fibrosis Admitted to PICUs. Pediatric Critical Care Medicine. 2020 Oct;21(10):e879-87. doi: 10.1097/PCC.0000000000002358. PMID: 32304511; PMCID: PMC7597545.

Huff N, Slain K, Clayton J, Shein S. 333: Trends in Epidemiology of Critically Ill Children in a Large National Database in the United States. Critical Care Medicine. 2020 Jan;48(1):149. doi: 10.1097/01.ccm.0000619688.58812.90.

Moffitt C, Deakins K, Cheifetz I, Clayton J, Slain K, Shein S. Use of Negative Pressure Ventilation in Pediatric Critical Care: Experience in 56 PICUs in the Virtual Pediatric Systems Database (2009-2019). Pediatric Critical Care Medicine. 2021 Jun 1;22(6):e363-8. doi: 10.1097/PCC.0000000000002690.

Sachdeva R, Rice TB, Reisner B, Brundage N, Hulbert C, Kaminski A, Wetzel RC. The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs. Pediatric Critical Care Medicine. 2020 Jul 8;1(1): e643-50. doi: 10.1097/PCC.0000000000002510. PMID: 32649399; PMCID: PMC7340137.

Dziorny AC, Lindell RB, Bennett TD, Bailey LC. Joining Datasets Without Identifiers: Probabilistic Linkage of Virtual Pediatric Systems and PEDSnet. Pediatr Crit Care Med. 2020;21(9):e628-e34. doi:10.1097/PCC.0000000000002380.

Sachdeva R, Rice TB, Reisner B, Brundage N, Hulbert C, Kaminski A, Wetzel RC. The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs. Pediatric critical care medicine. a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2020;21(9), e643–50. doi: https://doi.org/10.1097/PCC.0000000000002510.

Loomba RS, Villarreal EG, Farias JS, Bronicki RA, Flores S. Pediatric Intensive Care Unit Admissions for COVID-19: Insights Using State-Level Data. Int J Pediatr. 2020 Nov 18;2020:9680905. doi: 10.1155/2020/9680905. PMID: 33299428; PMCID: PMC7704189.

Tripathi S, Swayampakula AK, Deshpande GG, et al. Illustration of the current practice and outcome
comparison of early versus late tracheostomy after pediatric ECMO. Int J Artif Organs. 2020; Mar
31:391398820913571. [Epub ahead of print]

Lindell RB, Nishisaki A, Weiss SL, Traynor DM, Fitzgerald JC. Risk of Mortality in Immunocompromised
Children With Severe Sepsis and Septic Shock [published online ahead of print, 2020 Apr 14]. Crit Care
Med. 2020;10.1097/CCM.0000000000004329. doi:10.1097/CCM.0000000000004329

Leimanis Laurens, Mara PhD1,2; Snyder, Kristen MD3; Davis, Alan T. PhD4,5; Fitzgerald, Robert K.
MD1,2; Hackbarth, Richard MD1,2; Rajasekaran, Surender MD, MPH1,2 Racial/Ethnic Minority
Children With Cancer Experience Higher Mortality on Admission to the ICU in the United States,
Pediatric Critical Care Medicine: April 22, 2020 – Volume Online First – Issue – doi:
10.1097/PCC.0000000000002375

Dziorny, Adam C. MD, PhD1,2; Lindell, Robert B. MD2; Bennett, Tellen D. MD, MS3; Bailey, L. Charles
MD, PhD1,4 Joining Datasets Without Identifiers, Pediatric Critical Care Medicine: June 8, 2020 –
Volume Online First – Issue – doi: 10.1097/PCC.0000000000002380

2019

Goday P, Kuhn E, Mikhailov T. Early Parenteral Nutrition in Critically Ill Children not receiving Early
Enteral Nutrition is Associated with Significantly Higher Mortality. JPEN. Epub 2019 Oct.26
.https://doi.org/10.1002/jpen.1731

Balakrishnan B, Flynn-O’Brien KT, Simpson PM, Dasgupta M, Hanson SJ. Enteral Nutrition Initiation in
Children Admitted to Pediatric Intensive Care Units After Traumatic Brain Injury. Neurocrit Care.
2019;30(1) 193-200. doi:10.1007/s12028-018-0597-6. PMID: 30171446.

Ross PA, Newth CJ, Leung D, et al.Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic
Shock: A Retrospective Cohort Study. Journal of Pediatrics 2019;210, Pages 178–183.e2. DOI:

Ramsey N. Guffey D. Anagnostou K. Coleman N. Davis C. Epidemiology of Anaphylaxis in Critically Ill
Children in the United States. The Journal Of Allergy and Immunology. 2019: 7(7); 2241-2249.

Typpo K, Watson RS, Bennett TD, Farris RWD, Spaeder MC, Petersen NJ; Pediatric Existing Data
Analysis (PEDAL) Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI)
Network. Outcomes of Day 1 Multiple Organ Dysfunction Syndrome in the PICU. Pediatr Crit Care Med.
2019 Oct;20(10):914-922. doi: 10.1097/PCC.0000000000002044.

Lindell Robert B, Nishisaki Akira, Weiss Scott L, Balamuth Fran, Traynor Danielle M, Chilutti Marianne
R, Grundmeier Robert W, Fitzgerald Julie C: Comparison of Methods for Identification of Pediatric
Severe Sepsis and Septic Shock in the Virtual Pediatric Systems Database. Critical care medicine
47(2): e129-e135, Feb 2019. PMCID: PMC6336511

2018

Early Enteral Nutrition Is Associated With Significantly Lower Hospital Charges in Critically Ill Children
Theresa A. Mikhailov, MD,PhD 1; Shira J. Gertz, MD 2; Evelyn M. Kuhn,PhD 3; Matthew C. Scanlon,
MD 1; Thomas B. Rice, MD 1; and Praveen S. Goday, MBBS 4 Journal of Parenteral and Enteral
Nutrition Volume 00 Number 0 xxx 20181–6 C ? 2018 American Society for Parenteral and Enteral
Nutrition DOI: 10.1002/jpen.1025

Bigelow AM, Flynn-O’Brien KT, Simpson PM, Dasgupta M, Hanson SJ.
Multicenter Review of Current Practices Associated With Venous Thromboembolism Prophylaxis in
Pediatric Patients After Trauma. Crit Care Med. 2018;19(9):e448-e454. doi:
10.1097/PCC.0000000000001614.

Cole S. Wakeham M. Werlin S. Goday P. Classification and Nutrition Management of Acute
Pancreatitis in the Pediatric Intensive Care Unit. JPGN. 2018;67(6) 755-590. doi:
10.1097/MPG.0000000000002147

Tran M, Shein SL, Ji X, Ahuja SP. Identification of a “VTE-rich” population in pediatrics – Critically ill
children with central venous catheters. Thrombosis Research. 2018;161:73-77.
doi:10.1016/j.thromres.2017.11.014.

Halvorson E, Case D, Skelton J, McCrory M. Vascular Access in Critically Ill Pediatric Patients With
Obesity. Pediatric Critical Care Medicine. 2018;19(1):1-8. doi:10.1097/PCC.0000000000001368

Görges M, Peters C, MD, Murthy S, Pi S, Kissoon N. External Validation of the “Quick” Pediatric
Logistic Organ Dysfunction-2 Score Using a Large North American Cohort of Critically Ill Children With
Suspected Infection. PCCM. 2018; 19(12). DOI: 10.1097/PCC.0000000000001729

Peters C, Murthy S, Brant R, Kissoon N, Görges M. Mortality Risk Using a Pediatric Quick Sequential
(Sepsis-Related) Organ Failure Assessment Varies With Vital Sign Thresholds. Crit Care Med. 2018
Aug;19(8):e394-e402. doi: 10.1097/PCC.0000000000001598.

Renal Replacement Therapy Modalities in Critically Ill Children
Fernando Beltramo, MD1; Joseph DiCarlo, MD1; Joshua B. Gruber, MSPH3; Thom Taylor, PhD3;
Balagangadhar R. Totapally, MD2 Pediatric Critial Care Medicine: 2018 XXX 2018 • Volume XX •
Number XXX
DOI: 10.1097/PCC.0000000000001754

Balkin EM, Steurer MA, Delagnes EA, et al. Multicenter mortality and morbidity associated with
pulmonary hypertension in the pediatric intensive care unit. Pulmonary Circulation. 2018.
doi:10.1177/2045893217745785. Epub 2017 Dec 18.

Balkin E, Zinter M, Rajagopal S, Keller R, Fineman J, Steurer M. Intensive Care Mortality Prognostic
Model for Pediatric Pulmonary Hypertension. Pediatr Crit Care Med. 2018 June 19. [Epub ahead of
print]

Balakrishnan B, Zhang L, Simpson P, Hanson S. Impact of the Timing of Placement of an Intracranial
Pressure Monitor on Outcomes in Children with Severe Traumatic Brain Injury. Pediatr Neurosurg
2018;53:379–386https://doi.org/10.1159/000494028

Gupta P, Rettiganti M, Gosset JM, Daufeldt J, Rice TB, Wetzel RC. Development and Validation of an
Empiric Tool to Predict Favorable Neurologic Outcomes Among PICU Patients. Critical Care Medicine.
2018;46(1):108-115. doi:0.1097/CCM.0000000000002753. [Epub ahead of print 2017 Oct 6]

D. Hill, Garick & S. Ghanayem, Nancy & Hraska, Viktor & Jacobsen, Roni & Mitchell, Michael & Woods,
Ronald & Ginde, Salil. (2018). Variation in the use of Fontan fenestration in the current surgical era.
Progress in Pediatric Cardiology. 10.1016/j.ppedcard.2018.08.007.

Gupta P, Rettiganti M, Shinkawa T, Gossett JM, Brundage N, Jeffries HE, Bertrandt R.Reclassifying by
highest complexity operation rather than first operation influences mortality after pediatric heart surgery.
J Thorac Cardiovasc Surg. 2018 Jul 18. pii: S0022-5223(18)31780-X. doi: 10.1016/j.jtcvs.2018.06.035.

[Epub ahead of print]
Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric
Intensive Care Unit
Laura S. Peterson, MD, Cecilia Gállego Suárez, MD, Hannah E. Segaloff, MPH, …
First Published February 22, 2018 Research Article
Article information
Journal of Intensive Care Medicine, Article first published online: February 22, 2018
Received: December 22, 2017; Revisions received: January 07, 2018; Accepted: January 31, 2018

Laura S. Peterson, MD1, Cecilia Gállego Suárez, MD2, Hannah E. Segaloff, MPH3, Cameron Griffin,
BS2, Emily T. Martin, PhD, MPH3, Folafoluwa O. Odetola, MD, MPH4, Kanakadurga Singer, MD2
Reiter PD, Roth J, Wathen B, Lavelle J, Ridall LA. Low-Dose Epinephrine Boluses for Acute
Hypotension in the PICU*. Pediatric Critical Care Medicine. 2018;19(4):281-286.
doi:10.1097/pcc.0000000000001448.

Kolovos, Nikoleta & Gill, Jeff & H. Michelson, Peter & Doctor, Allan & E. Hartman, Mary. (2018).
Reduction in Mortality Following Pediatric Rapid Response Team Implementation. Pediatric Critical
Care Medicine. 19. 1. 10.1097/PCC.0000000000001519.

2017

Edwards JD, Lucas AR, Boscardin WJ, Dudley RA. Repeated critical illness and unplanned
readmissions within 1 year to PICUs. Critical Care Medicine 2017; 45(8):1276-1284.

Flynn-O’Brien K, Fallat M, Rivera F, et al. Pediatric Trauma Assessment and Management Database:
Leveraging Existing Data Systems to Predict Mortality and Functional Status after Pediatric Injury.
Journal Of The American College Of Surgeons. 2017;224:933-944.

Geneslaw A, Jia J, Lucas R, Agus M. Pediatric Intermediate Care and Pediatric Intensive Care Units:
PICU Metrics and an Analysis of Patients that use Both. Journal of Critical Care. 2017;41:268-274.
doi:DOI: .

Ortmann LA, Manimtim WM, Lachica CI. Outcomes of Tracheostomy in Children Requiring Surgery for
Congenital Heart Disease. Pediatric Cardiology. 2017;38(2):296-301. doi:10.1007/s00246-016-1512-6.
Original Article First Online: 21 November 2016

McCrory MC, Spaeder MC, Gower EW, Nakagawa TA, et al. Time of Admission to the PICU and
Mortality. Pediatric Critical Care Medicine. 2017;18(10):915-923. doi:10.1097/PCC.0000000000001268
Feature Article .

Patel MM, Travers CD, Stockwell JA, Geller RJ, Kamat PP, Grunwell JR. Analysis of Interventions
Required in 12,021 Children With Acute Intoxications Admitted to PICUs. Pediatric Critical Care
Medicine. 2017;18(7):e281-e289. doi:10.1097/PCC.0000000000001187.

Russell R, Rettiganti M, Brundage N, Jeffries H, Gupta P. Performance of Pediatric Risk of Mortality
Score Among Critically Ill Children With Heart Disease. World Journal for Pediatric and Congenital
Heart Surgery . 2017;8(4):427-434. doi:10.1177/2150135117704656 .

Doctor A, Zimmerman J, Agus M, et al. Pediatric Multiple Organ Dysfunction Syndrome: Promising
Therapies. Pediatric Critical Care Medicine. 2017;18(3):S67-S82. doi:10.1097/pcc.0000000000001053.

Shein SL, Slain KN, Clayton JA, Mckee B, Rotta AT, Wilson-Costello D. Neurologic and Functional
Morbidity in Critically Ill Children With Bronchiolitis*. Pediatric Critical Care Medicine. 2017;18(12):1106-
1113. doi:10.1097/pcc.0000000000001337.

Edwards JD, Lucas AR, Boscardin WJ, Dudley RA. Repeated Critical Illness and Unplanned
Readmissions Within 1 Year to PICUs*. Critical Care Medicine. 2017;45(8):1276-1284.
doi:10.1097/ccm.0000000000002439.

Leroue MK, Good RJ, Skillman HE, Czaja AS. Enteral Nutrition Practices in Critically Ill Children
Requiring Noninvasive Positive Pressure Ventilation*. Pediatric Critical Care Medicine.
2017;18(12):1093-1098. doi:10.1097/pcc.0000000000001302.

2016

Edwards J, Houtrow A, Lucas A, et al. Children and Young Adults who Received Tracheostomies or
were Initiated on Long-Term Ventilation in Pediatric ICUs. Pediatric Critical Care Medicine.
2016;17(8):e324-334.

Gall C, Wetzel R, Kolker A, Kanter RK. Pediatric Triage in a Severe Pandemic: Maximizing Survival by
Establishing Triage Thresholds. Critical Care Medicine. 2016;44(9):1762-1768.
doi:10.1097/CCM.0000000000001759.

Flynn-O’Brien KT, Fallat ME, Rice TB, Rivera R. Improving Risk-Adjusted Mortality Modeling in
Pediatric Trauma with a Novel Dataset. Pediatrics. 2016;137:270A.
doi:10.1542/peds.137.Supplement_3.270A .

Coro MD, Spaeder MC, Penk JS, Levin AB, Futterman C,
Unscheduled Pediatric Intensive Care Unit Admissions in Patients With Cardiovascular Disease:
Clinical Features and Outcomes. World J Pediatr Congenit Heart Surg. 2016;7(4):454-9. doi:
10.1177/2150135116648308.

Coro M, Spaeder M, Penk J, Levin A, Futterman C. Unscheduled Pediatric Intensive Care Unit
Admissions in Patients with Cardiovascular Disease, Clinical Features and Outcomes. World Journal
for Pediatric and Congenital Heart Surgery. 2016; 7(4): 454-459. doi: 10.1177/2150135116648308.

Meyer M, Mikhailov T, Kuhn E, Collins M, Scanlon M. Pediatric Specialty Transport Teams are not
Associated with Decreased 48-Hour Pediatric Intensive Care Unit Mortality: A Propensity Analysis of
the VPS, LLC Database. Air Medical Journal. 2016;35(2): 73-78. doi:

Field-Ridley A, Dharmar M, Steinhorn D, McDonald C, Marcin J. ICU-Acquired Weakness is
Associated with Differences in Clinical Outcomes in Critically Ill Children. Pediatr Crit Care Med.
2016;17(1):53-7. doi: 10.1097/PCC.0000000000000538.

Gall C, Wetzel R, Kolker A, Kanter R, Toltzis P. Pediatric Triage in a Severe Pandemic: Maximizing
Survival by Establishing Triage Thresholds. Critical Care Medicine. 2016;44(9):1762-1768(7). DOI:

Gupta P, Rettiganti M, Rice T, Wetzel R. Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes
in Pediatric Intensive Care: A Multi-Center Study. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead
of print]. doi:10.1164/rccm.201512-2456OC.

McCrory MC, Lee KJ, Scanlon MC, Wakeham MK. Predictors of need for mechanical ventilation at
discharge after tracheostomy in the PICU. Pediatric Pulmonology. 2016;51(1):53-59.
doi:10.1002/ppul.23195. Epub 2015 Mar 30.

Heneghan J, Lansell A, Domowicz D, Shein S. Intensive Care Unit Readmissions Among Children with
Tracheostomies Placed Following Cardiac Arrest. Pediatrics. 2016;137:258A-258A.
doi:10.1542/peds.137.Supplement_3.258A.

Edwards J, Houtrow A, Vasilevskis E, et al. Children and Young Adults who receive tracheostomies or
were intubated on Long Term Ventilation in the Pediatric ICU. PCCM. 2016; 17(8): e324-34. doi:
10.1097/PCC.0000000000000844.

Gupta P, Rettiganti M, Gossett JM, Yeh JC. Risk factors for mechanical ventilation and reintubation
after pediatric heart surgery. Journal Thoracic Cardiovascular Surgery. 2016;151(2):451-458.
doi:10.1016/j.jtcvs.2015.09.080. Epub 2015 Sep 28

Gupta P, Rettiganti M, Jeffries H, Rice T. Epidemiology of Reintubation Among Children Undergoing
Heart Operations of Varying Complexity. Critical Care Medicine. 2016;44(12):126.
doi:10.1097/01.ccm.0000508876.60312.35 .

Gupta P, Rettiganti M, Jeffries H, et al. Association of 24/7 In-house ICU Attending Coverage with
Outcomes in Children Undergoing Heart Operations. Ann Thorac Surg. (Accepted for Publication, In
Press). Ann Thorac Surg. 2016 Jun 18. [Epub ahead of print].

Gupta P, Rettiganti M, Rice TB, Wetzel RC. Impact of 24/7 In-Hospital Intensivist Coverage on
Outcomes in Pediatric Intensive Care. A Multicenter Study. American Journal of Respiratory and Critical
Care Medicine. 2016;194(12). doi:10.1164/rccm.201512-2456OC .

Gupta P, Rettiganti M, Jeffries H, et al. Risk Factors and Outcomes of In-Hospital Cardiac Arrest
Following Pediatric Heart Operations of Varying Complexity. Resuscitation. 2016 May 13;105:1-7.
[Epub ahead of print]. doi: 10.1016/j.resuscitation.2016.04.022.

Gupta P, Tang X, Rettiganti M, et al. Association of House Staff Training with Mortality in Children with
Critical Illness. Acta Paediatrica. 2016;105(2): e60–e66, doi: 10.1111/apa.13223.

Ross P, Newth C, Leung D, Wetzel R, Khemani R. Obesity and Mortality Risk in Critically Ill Children.
Pediatrics. 2016;137(3):e20152035. Epub 2016 Feb 16. doi: 10.1542/peds.2015-2035.

Obesity and Mortality Risk in Critically Ill Children
Patrick A. Ross, Christopher J.L. Newth, Dennis Leung, Randall C. Wetzel, Robinder G. Khemani
COMPARING COMPLICATION RATES IN CENTRAL LINES VERSUS PERIPHERALLY INSERTED
CENTRAL CATHETERS

Noonan, Patrick; Petersen, Tara; Hanson, Sheila; Simpson, Pippa; Dasgupta, Mahua
Critical Care Medicine: December 2016 – Volume 44 – Issue 12 – p 346
doi: 10.1097/01.ccm.0000509756.02057.eb

Gupta P, Richardson T, Hall M, et al. Effect of Inhaled Nitric Oxide on Outcomes in Children with Acute
Lung Injury: Propensity Matched Analysis from a Linked Database. Crit Care Med. 2016 May 9. [Epub
ahead of print]. doi: 10.1097/CCM.0000000000001837.

Gupta P, Rettiganti M, Fisher P, Chang A, Rice T, Wetzel R. Association of Freestanding Children’s
Hospitals with Outcomes in Children with Critical Illness. Crit Care Med. 2016 Aug 4. [Epub ahead of
print]. doi:10.1097/CCM.0000000000001961.

Markovitz B, Kukuyeva I, Soto-Campos G, Khemani R. PICU Volume and Outcome: A SeverityAdjusted Analysis. PCCM. 2016;17(6):483-9. doi: 10.1097/PCC.0000000000000697.

Markovitz BP, Kukuyeva I, Soto-Campos G, Khemani RG. PICU Volume and Outcome: A SeverityAdjusted Analysis. Pediatric Critical Care Medicine. 2016;17(6):483-489.
doi:10.1097/pcc.0000000000000697.

2015

Tolzis P, Soto-Campos G, Kuhn E, Hahn R. Evidence-Based Pediatric Outcome Predictors to Guide
the Allocation of Critical Care Resources in a Mass Casualty Event. Pediatric Critical Care Medicine.
2015;16(7).

Zinter MS, Dvorak CC, Spicer A, Cowan MJ. New Insights Into Multicenter PICU Mortality Among
Pediatric Hematopoietic Stem Cell Transplant Patients. Critical Care Medicine. 2015;43(9):1986-1994.

Flynn-O’Brien KT, Thompson LL, Gall CM, Fallat ME. Variability in the structure and care processes for
critically injured children: A multicenter survey of trauma bay and intensive care units. Journal of
Pediatric Surgery. 2016;51(3):490-498. doi:10.1016/j.jpedsurg.2015.09.006 | .

Gupta P, Tang X, Gossett J, et al. Variation of Ventilation Practices with center volume after pediatric
heart surgery. Clin Cardiol. 2015;38(3):178-84. doi: 10.1002/clc.22374. Epub 2015 Feb 23.

Goday PS, Wakeham M, Kuhn EM, Collins MM. Acute Pancreatitis in the Pediatric Intensive Care Unit.
JPGN. 2015;61(1):108-112. doi:10.1097/MPG.0000000000000780.

APA Toltzis, Philip MD1; Soto-Campos, Gerardo PhD2; Kuhn, Evelyn M. PhD3; Hahn, Ryan DO1;
Kanter, Robert K. MD4,5; Wetzel, Randall C. MD2,6 Evidence-Based Pediatric Outcome Predictors to
Guide the Allocation of Critical Care Resources in a Mass Casualty Event*, Pediatric Critical Care
Medicine: September 2015 – Volume 16 – Issue 7 – p e207-e216
doi: 10.1097/PCC.0000000000000481

Gupta P, Tang X, Rettiganti M, Lauer C. Association of house staff training with mortality in children
with critical illness. Acta Paediatrica. 2015;105(2):e60-e66. doi:10.1111/apa.13223.

Zinter MS, Dvorak CC, Spicer A, Cowan MJ, Sapru A. New insights into multicenter PICU mortality
among pediatric hematopoietic stem cell transplant patients. Crit Care Med 2015;43(9): 1986-1994.
PMID: 26035280

Heneghan J, Lansell A, Lopez-Domowicz D, Shein S. ICU Readmissions for Children with
Tracheostomies Places Following Cardiac Arrest. Critical Care Medicine. 205AD;43(12):185.
doi:10.1097/01.ccm.0000474563.43840.25.

Edwards J, Vasilevskis E, Yoo E, et al. Adults with childhood-onset chronic conditions admitted to US
pediatric and adult intensive care units. J Crit Care. 2015 Feb;30(1):201-6. doi:
10.1016/j.jcrc.2014.10.016. Epub 2014 Oct 25.

Anand K, Sepanski R, Giles K, et al. Pediatric Intensive Care Unit Mortality Among Latino Children
Before and After a Multilevel Health Care Delivery Intervention. JAMA Pediatr. 2015 Feb 23. doi:
10.1001/jamapediatrics.2014.3789. [Epub ahead of print]

Kanwaljeet J. S. Anand, MBBS, DPhil; Robert J. Sepanski, MS; Kimberley Giles, MBA, MSHA; Samir
H. Shah, MD, MBA, FRCPC; Paul D. Juarez, PhD, Pediatric Intensive Care Unit Mortality Among Latino
Children Before and After a Multilevel Health Care Delivery Intervention. JAMA Pediatr.
2015;169(4):383-390. doi:10.1001/jamapediatrics.2014.3789

Toltzis P, Soto-Campus G, Kuhn E, Hahn R, Kanter R, Wetzel R. Evidence-Based Pediatric Outcome
Predictors to Guide the Allocation of Critical Care Resources in a Mass Casualty Event. Pediatr Crit
Care Med. 2015;16(7):e207–e216. doi: 10.1097/PCC.0000000000000481

Jeffries H, Soto-Campos G, Katch A, Gall C, Rice T, Wetzel R. A Pediatric Index of Cardiac Surgical
Intensive Care Mortality Risk Score for Pediatric Cardiac Critical Care. Pediatr Crit Care Med.
2015;16(9):846–852. doi: 10.1097/PCC.0000000000000489.

Nguyen T, Bhalla A, Leung D, Khemani R, Ross P. PICU Mortality and Body Habitus in Patients with
Septicemia or Septic Shock. Critical Care Medicine.2015;43(12):253–254. doi:
10.1097/01.ccm.0000474839.78529.93

2014

Panchal AK, Manzi J, Connolly S, Christensen M, Wakeham M, Goday PS, Mikhailov TA. Safety of
Enteral Feedings in Critically Ill Children Receiving Vasoactive Agents. JPEN J Parenter Enteral Nutr.
2014 Aug 28. pii: 0148607114546533.

Mikhailov, T, Kuhn, E, Manzi,, J, et al. Early enteral nutrition is associated with lower mortality in
critically ill children. JPEN J Parenter Enteral Nutr. 2014 May;38(4):459-66. doi:
10.1177/0148607113517903. Epub 2014 Jan 8.

Russell, R, Ghanayem, N, Kuhn, E, Jeffries, H, Scanlon, M, & Rice, T. Relationship between riskadjustment. World Journal for Pediatric and Congenital Heart Surgery, World J Pediatr Congenit Heart
Surg. 2014 Jan 1;5(1):16-21. doi: 10.1177/2150135113510008.

Gupta P, Green J, Tang X, et al. Comparison of high-frequency oscillatory ventilation and conventional
mechanical ventilation in pediatric respiratory failure. JAMA Pediatr. 2014 Mar;168(3):243-9, doi:
10.1001/jamapediatrics.2013.4463

Iannucci G, Oster M, Chanani N, et al. The Relationship between In-House Attending Coverage and
Duration of Mechanical Ventilation Following Congenital Heart Surgery, Pediatr Crit Care Med. 2014
Mar;15(3):258-63. doi: 10.1097/PCC.0000000000000068

Wakeham M, Kuhn E, Lee J, McCrory M, Scanlon M, Use of Tracheostomy in the Pediatric Intensive
Care Unit among Patients Requiring Prolonged Mechanical Ventilation.Intensive Care Med 2014
Jun;40(6)863-70.doi: 10.1007/s00134-014-3298-4. Epub 2014 May 1

Gaies M, Jeffries H, Niebler R, et al. Vasoactive-Inotropic Score Is Associated with Outcome After
Infant Cardiac Surgery: An Analysis From the Pediatric Cardiac Critical Care Consortium and Virtual
PICU System Registries. PCCM 2014. 15 (6). pp529-537. DOI: 10.1097/PCC.0000000000000153

Gupta P, Tang X, Gossett J, et al. Association of center volume with outcomes in critically ill children
with acute asthma. Ann Allergy Asthma Immunol. 2014 Jul;113(1):42-7. doi:
10.1016/j.anai.2014.04.020. Epub 2014 May 14.

Panchal A, Manzi J, Connolly S, et al., Safety of Enteral Feedings in Critical Ill Children on Vasoactive
Agents. JPEN J Parenter Enteral Nutr. 2014 Aug 28. pii: 0148607114546533. [Epub ahead of print]

Gupta P, Kacmarek RM, Wetzel RC. It is Too Eartly to declare Early or Late Rescue High-Frequency
Oscillatory Ventilation Dead- Reply. JAMA Pediatr. 2014; 168(9): 863. doi:

Bone, M, Feinglass, J, Goodman, D. Risk Factors for Acquiring Functional and Cognitive Disabilities
During Admission to a PICU. Pediatr Crit Care Med. 2014 Sep;15(7):640-8. doi:
10.1097/PCC.0000000000000199

Zinter M, DuBois S, Spicer A, et al. Pediatric cancer type predicts infection rate, need for critical care
intervention, and mortality in the pediatric intensive care unit. Intensive Care Med. 2014
Oct;40(10):1536-44. doi: 10.1007/s00134-014-3389-2. Epub 2014 Jul 15. PMID: 25023526.

Gupta P, Tang X, Gall C, et al. Epidemiology and outcomes of in-hospital cardiac arrest in critically ill
children across hospitals of varied center volume: a multi-center analysis. Resuscitation. 2014
Nov;85(11):1473-9. doi: 10.1016/j.resuscitation.2014.07.016. Epub 2014 Aug 7.

McCrory M, Gower E, Simpson S, Nakagawa T, Mou S, Morris P, et al.. Off-Hours Admission to
Pediatric Intensive Care and Mortality.Pediatrics. Pediatrics. 2014 Nov;134(5):e1345-53. doi:
10.1542/peds.2014-1071. Epub 2014 Oct 6.

2013

Wakeham M, Christensen M, Manzi J, Kuhn EM, Scanlon M, Goday PS, Mikhailov TA. Registered
dietitians making a difference: early medical record documentation of estimated energy requirement in
critically ill children is associated with higher daily energy intake and with use of the enteral route.
Acad Nutr Diet. 2013 Oct;113(10):1311-6. doi: 10.1016/j.jand.2013.04.025. Epub 2013 Jun 28.

Edwards JD, Lucas AR, Stone PW, Boscardin WJ, Dudley RA. Frequency, risk factors, and outcomes
of early unplanned readmissions to PICUs. Critical Care Medicine 2013; 41(12):2773-2783.

Czaja, A, Hosokawa, P, & Henderson, W. Unscheduled readmissions to the picu: epidemiology, risk
factors, and variation among centers. Pediatr Crit Care Med., 2013 Jul;14(6):571-9. doi:
10.1097/PCC.0b013e3182917a68.

Edwards J, Houtrow A, Vasilevskis E, Dudley R, Okumura M; A multi-institutional profile of adults
admitted to pediatric intensive care units, JAMA Pediatr. 2013 May;167(5):436-43. doi:
10.1001/jamapediatrics.2013.1316

Cassidy, L, Lambropoulos, D, Enters, J, Farahzad, M, Gourlay, D, Lal, D, Health Disparities Analysis of
Critically Ill Pediatric Trauma Patients in Milwaukee, Wisconsin, J Am Coll Surg. 2013 Aug;217(2):233-
9. doi: 10.1016/j.jamcollsurg.2013.02.032. Epub 2013 May 8

Ghuman, A, Newth, C, Khemani, R. Impact of Gender on Sepsis Mortality and Severity of Illness for
Prepubertal and Postpubertal Children. The Journal of Pediatrics Sept 2013.163(3),pgs 835-840.e1

Edwards J, Lucas A, Stone P, Boscardin W, Dudley R, Frequency, Risk Factors, and Outcomes of
Early Unplanned Readmissions to PICUs. Crit Care Med. 2013 Dec;41(12):2773-83. doi:
10.1097/CCM.0b013e31829eb970.

Shibata, S, Khemani, R, Markovitz, B. Patient Origin Is Associated With Duration of Endotracheal
Intubation and PICU Length of Stay for Children With Status Asthmaticus. J Intensive Care Med. 2014
May-Jun;29(3):154-9. doi: 10.1177/0885066613476446. Epub 2013 Feb 11

2012

Ingaramo, O., Khemani, R., Markovitz, B, Epstein, D, Effect of race on the timing of the Glenn and
Fontan procedures for single-ventricle congenital heart disease, Pediatr Crit Care Med. 2012;13(2):174-
7. doi: 10.1097/PCC.0b013e3182231862.

Weiss, S, Parker, B, Bullock, M, et al, Defining pediatric sepsis by different criteria: Discrepancies in
populations and implications for clinical practice, Pediatr Crit Care Med. 2012 Jul;13(4):e219-26. doi:
10.1097/PCC.0b013e31823c98da.

Edwards J, Houtrow (A, Vasilevskis E, et al, Chronic conditions among children admitted to U.S.
pediatric intensive care units: their prevalence and impact on risk for mortality and prolonged length of
stay. Crit Care Med. 2012 Jul;40(7):2196-203.

Sala, K, Karamessinis L, Zucker A, Carroll C. Respiratory Failure in Children with Status Asthmaticus: A
Review of the VPS Database. Pediatric Allergy, Immunology, and Pulmonology. 2012;25(4): 226-230.
doi:10.1089/ped.2012.0188.

2011

Schindler C, Mikhailov T, Kuhn E, et al . Protecting Fragile Skin: Nursing Interventions to Decrease
Development of Pressure Ulcers in Pediatric Intensive Care. Am J Crit Care. 2011;20(1):26-35.

Czaja AS, Scanion MC, Kuhn EM, Jeffries HE. Performance of the Pediatric Index of Mortality 2 for
pediatric cardiac surgery patients. Pediatric Critical Care Medicine. 2011;12(2):184-189.
doi:10.1097/PCC.0b013e3181e89694.

Epstein D, Wong C, Khemani R, et al. Race/Ethnicity is not associated with mortality in the PICU.
Pediatrics. Pediatrics: 2011;127(3):e588-97. Doi: 10.1542/peds. 2010-0394 Epub 2011 Feb 28.

Deeter K, King M, Ridling D, Irby G, Lynn A, Zimmerman J. Successful Implementation of a Pediatric
Sedation Protocol For Mechanically Ventilated Patients. Crit Care Med. 2011;39(4):683-8. doi:
10.1097/CCM.0b013e318206cebf

Faustino, E, Lawson, K, Northrup V, Higgerson R, Mortality-adjusted Duration of Mechanical Ventilation
in Critically Ill Children with Symptomatic Central Venous Line-Related Deep Venous Thrombosis. Crit
Care Med. 2011;39(5):1151-6. doi: 10.1097/CCM.0b013e31820eb8a1

Wetzel, R, Sachdeva, R, Rice, T, Are all ICUs the same?. Paediatr Anaesth. 2011;21(7):787-93. doi:
10.1111/j.1460-9592.2011.03595.x. Epub 2011 May 9

Hanson, S, Lawson, K, Brown A, et al, Current Treatment of Venous Thromboembolism in Children
Admitted to Pediatric Intensive Care Units. Paediatr Anaesth. 2011;21(10):1052-7. doi: 10.1111/j.1460-
9592.2011.03653.x. Epub 2011 Jul 18

Higgerson, R, Laswon, K, Christie, L, et al, Incidence and Risk Factors Associated with Venous
Thrombotic Events in Pediatric ICU Patients. Pediatr Crit Care Med. 2011;12(6):628-34.
doi:10.1097/PCC.0b013e318207124a

Niedner MF, Huskins WC, Colantuoni E, et al. Epidemiology of central line-associated bloodstream
infections in the pediatric intensive care unit. Infection Control and Hospital Epidemiology.
2011;32(12):1200-1208. doi: 10.1086/662621.

2010

Lee K, Tieves K, Scanlon M. Alterations in end-of-life support in the pediatric intensive care unit.
Pediatrics. 2010 Oct; 126(4):e859-64. Epub 2010 Sep 6. Doi: 101542/pedS2010-2014.

2009

Gorman M, Sachdeva R, Rice T, Wetzel R., Support for PICUs and the PRISM scoring algorithms,
Pediatr Crit Care Med. 2009;10(1):143-4. doi: 10.1097/PCC.0b013e3181937bf4

Goday PS, Vermilyea S, Kuhn EM, Otto MM, Mikhailov TA. Admission Anthropometric Measures and
Outcomes in the Pediatric Intensive Care Unit (PICU). Journal of Parenteral and Enteral Nutrition.
2009;33(2):237-238.

Typpo K, Petersen N, Hallman D, Markovitz B, Mariscalco M, Day 1 multiple organ dysfunction
syndrome is associated with poor functional outcome and mortality in the pediatric intensive care unit,
Pediatr Crit Care Med. 2009;10(5):562-70.

2008

Goday PS. Does admission weight influence mortality and morbidity in the pediatric intensive care unit
(PICU)? Journal of Parenteral Enteral Nutrition. 2008;32(3):316-317.

Odetola F, Rosenberg A, Davis M, Clark S, Dechert R, Shanley T., Do outcomes vary according to the
source of admission to the pediatric intensive care unit? Pediatr Crit Care Med. 2008;9(1):20-5. Doi:
10.1097/01.PCC.0000298642.11872:29.

LaRovere J, Jeffries H, Sachdeva R, et al, Databases for assessing the outcomes of the treatment of
patients with congenital and paediatric cardiac disease–the perspective of critical care, Cardiol Young.
2008 Dec;18 Suppl 2:130-6. Doi: 10.1017/S1047951108002886

2007

Odetola F, Clark S, Dechert R, Shanley T.,Going back for more: an evaluation of clinical outcomes and
characteristics of readmissions to a pediatric intensive care unit., Pediatr Crit Care Med. 2007;
8(4):343-7; CEU quiz 357.

Schindler C, Mikhailov T, Fischer K, Lukasiewicz G, Kuhn E, Duncan L., Skin integrity in critically ill and
injured children. Am J Crit Care. 2007; 16(6):568-74.

2006

Sachdeva R, Wetzel R, Gorman M, Rice T. Public reporting of Outcomes, Medical Malpractice Trends
and Pediatric Intensive Care in the U.S. Pediatric Critical Care Medicine. 2006; 7(5): 515.

Sachdeva RC, Rice TB, Implementation of a validated Pediatric Critical Care Database for Quality and
Outcomes Assessment., Pediatric Critical Care Medicine. 2006;7(5):515.

Odetola F, Shanley T, Gurney J, et al. Characteristics and Outcomes of Interhospital Transfers from
level II to level I Pediatric Intensive Care units., Pediatr Crit Care Med. 2006;7(6):536-40.

2003

Kurachek S, Newth C, Quasney M, et al. Extubation failure in pediatric intensive care: a multiple-center
study of risk factors and outcomes. Crit Care Med. 2003;31(11):2657-64.