Abstracts

Abstracts Utilizing VPS Data

VPS is the Only Way to Truly Benchmark Your PICU’s Performance as a
Fundamental Requirement for Quality Improvement

2024

Spradley, Emily; Brintzenhoff, Rita; Rocio, Mata1; Brown, Karla; Spangler, Lacey; Thompson, Kyle; Evans, Susan. 1215: DECREASING TIME TO EXTUBATION WITH A COLLABORATIVE SPONTANEOUS BREATHING TRIAL ALGORITHM. Critical Care Medicine 52(1):p S579, January 2024. | DOI: 10.1097/01.ccm.0001003024.76697.7f

2022

Killien EY, Zahlan JM, Lad H, Watson RS, Vavilala MS, Huijsmans RLN, Rivara FP. Epidemiology and Outcomes of Multiple Organ Dysfunction Syndrome following Pediatric Trauma [abstract]. J Trauma Acute Care Surg. 2022 Apr 1;doi: 10.1097/TA.0000000000003616. Epub ahead of print. PMID: 35358103.

Brennan M, Lindell RB, Nishisaki A, Fitzgerald J, Dziorny AC. Application of Machine Learning in a Linked Multi-Center Dataset: Classifying MODS in Septic Shock [abstract]. Society for Critical Care Medicine (Accepted). 2022 Feb; doi: 10.1097/01.ccm.0000812072.99453.0e.

Nagpal A, Akande M, Muisyo T, Cutler J, Anderson M, Allen C. Children’s Hospital’s are Associated with Improved Outcomes in PICU Patients with Sepsis [abstract]. Critical Care Medicine. 2022 Jan;50(1):30. doi: 10.1097/01.ccm.0000806704.85710.54.

Holton C, Lee B, Bauer P. 49: Admission PaO2 and Mortality Among Pediatric ICU Patients and Critically Ill Subgroups [abstract]. Critical Care Medicine. 2022 Jan;50(1):25. doi: 10.1097/01.ccm.0000806660.40383.aa.

Fink D, Dingeldein M, Rose JA, Slain KN. Differences in Mortality by Race in a Cohort of Traumatically Injured Children Admitted to the Pediatric Intensive Care Unit [abstract]. Pediatrics. 2022 Feb 23;149:400

Lindell RB, Fitzgerald JC, Rowan CM, Flori HR, Di Nardo M, Napolitano N, Traynor DM, Lenz KB, Emeriaud G, Jeyapalan A, Nishisaki A. 510: Duration of Preintubation NIPPV is Associated with PICU Mortality in Immunocompromised Children [Abstract]. Critical Care Medicine. 2022 Jan;50(1):246. doi: 10.1097/01.ccm.0000808364.71604.3e.

Kingdon T*, Ross P, Newth CJL, Bhalla A. Obesity and Severity of Illness in Pediatric Status Asthmaticus. Chest. 2022; 162(4) S: A771.).

Gutzeit J, Ruiz J, Pan A, Mikhailov T, Simpson, P. 520: Pediatric intensive care length of stay for asthma: Does institution of origin contribute? [abstract]. Critical Care Medicine. 2022;50(1), 251.

Sachdeva R, Soto-Campos G, Brundage N, Rice T, Wetzel R. 492: Progression of RSV and Influenza Pediatric ICU Admissions by Geographic Regions in the U.S. [abstract]. Critical Care Medicine. 2022 Jan;50(1):237. doi: 10.1097/01.ccm.0000808292.80046.92.

Palumbo J, Soto-Campos G, Rice T, Wetzel R. 515: Determining Risk Factors and Predicting Extubation Failure Using Historical Data [abstract]. Critical Care Medicine. 2022;50(1):24.

Palumbo J, Soto-Campos G, Rice T, Wetzel R. 515: Determining Risk Factors and Predicting Extubation Failure Using Historical Data. Critical Care Medicine. 2022 Jan;50(1):249. doi: 10.1097/01.ccm.0000808384.60486.86.

2021

Duga M, Ari JB, Yacou M, Cross C. Outcomes of Children With Diabetic Ketoacidosis Necessitating Tracheal Intubation [abstract]. Critical Care Medicine. 2021 Jan; 49(1):218. doi: 10.1097/01.ccm.0000727708.56832.a9.

Mawby I, Ronith C, Aadi P, Sarisha M, Rupesh R. Acute Kidney Injury in COVID-19 Pediatric Patients: Analysis of the Virtual Pediatric System Data [abstract]. American Journal of Kidney Diseases. 2021;p 625. doi: https://doi.org/10.1053/j.ajkd.2021.02.192.

Palumbo J, Wetzel , Rice T, Soto-Campos G. A Predictive Model for Duration of Invasive Ventilation Using PIM3 and PRISM III Admisison Data [abstract]. Crit Care Med. 2021;49(1):245. doi: 10.1097/01.ccm.0000727916.13712.ad.

2020

Tripathi S, Swayampakula AK, Deshpande GG,  Michele A, Wang Y, Welke KF.   Illustration of the Current Practice and Outcome Comparison of Early Versus Late Tracheostomy After Pediatric ECMO [abstract]. Int J Artif Organs. 2020 Mar 31;43(11). [Epub ahead of print] doi:  https://doi.org/10.1177/0391398820913571

Moffitt C, Slain K, Deakins K, Speicher R, Shein S. 1177: Negative Pressure Ventilation in Pediatric Critical Care: Historical and Current Role and Implications for Future Study https://journals.lww.com/ccmjournal/Fulltext/2020/01001/1177__EPIDEMIOLOGY_AND_OUTCOMES_OF.1135.aspx  Epidemiology and Outcomes of Negative-pressure Ventilation Use in a Multicenter PICU Dataset  [abstract]. Critical Care Medicine. 2020 Jan;48(1):566. doi: 10.1097/01.ccm.0000643632.21028.4a.

Sachdeva R, Rice T, Soto-Campos G, Palumbo J, Brundage N, Reisner B, Wetzel R. 1273: Regional Variations in Pediatric Intensive Care Outcomes and Patterns of Use in the United States [abstract]. Critical Care Medicine. 2020 Jan;48(1):613. doi: 10.1097/01.ccm.0000645008.03082.ae.

2019

Lindell R, Nishisaki A, Weiss S, Traynor D, Fitzgerald J. 1679: Risk of Mortality in Immunocompromised Children With Severe Sepsis and Septic Shock [abstract]. Critical Care Medicine. 2019 Jan;47(1):813. doi: 10.1097/01.ccm.0000552418.70667.98.

McCluskey CK, Allareddy V, Rampa S, Allareddy V, Rotta AT. Characterization of Suicide and Deliberate Self-Harm Among Children in the United States [abstract]. Clinical Pediatrics (Phila). 2019 Jan;58(1):66-72. doi: 10.1177/0009922818806313. Epub 2018 Oct 19.

Palumbo J, Wetzel R, Soto-Campos G. A Model of New Morbidity in the ICU Based on PIM3 and PRISM III Factors and Functional Status Score [abstract]. Critical Care Medicine. 2019;48(1)245. doi: 10.1097/01.ccm.0000727916.13712.ad.

2018

Balakrishnan B, Zhang L, Simpson P, Hanson S. Impact of the Timing of Placement of an Intracranial
Pressure Monitor on Outcomes in Children with Severe Traumatic Brain Injury. Pediatr Neurosurg
2018;53:379–386https://doi.org/10.1159/000494028.

Mikhailov T, Gertz S, Kuhn E, Scanlon M, Rice T, Goday P. Early Enteral Nutrition Is Associated with
Significantly Lower Hospital Charges in Critically Ill Children. Journal of Parenteral and Enteral
Nutrition. American Society for Parenteral and Enteral Nutrition. 2018; 1–6 C DOI: 10.1002/jpen.1025

Bigelow A, Flynn-O’Brien K, Simpson P, Dasgupta M, Hanson S. Multicenter Review of Current
Practices Associated with Venous Thromboembolism Prophylaxis in Pediatric Patients After Trauma.
Pediatr Crit Care Med. 2018; Jun 15. doi: 10.1097/PCC.0000000000001614. [Epub ahead of print]

Tran M, Shein S, Ji X, Ahuja S. Identification of a “VTE-rich” population in pediatrics – Critically ill
children with Central Venous Catheters. Thrombosis Research. 2018;161:73-77.
doi:10.1016/j.thromres.2017.11.014.

Gupta P, Rettiganti M, Shinkawa T, Gossett JM, Brundage N, Jeffries HE, Bertrandt R. Reclassifying by
highest complexity operation rather than first operation influences mortality after pediatric heart surgery.

J Thorac Cardiovasc Surg. 2018 Jul 18. pii: S0022-5223(18)31780-X. doi: 10.1016/j.jtcvs.2018.06.035.
[Epub ahead of print]

Peters C, Murthy S, Brant R, Kissoon N, Görges M. Mortality Risk Using a Pediatric Quick Sequential
(Sepsis-Related) Organ Failure Assessment Varies With Vital Sign Thresholds. Crit Care Med. 2018
Aug;19(8):e394-e402. doi: 10.1097/PCC.0000000000001598.

Halvorson E, Case D, Skelton J, McCrory MC Vascular Access in Critically Ill Pediatric Patients With
Obesity. Pediatric Critical Care Medicine. 2018;19(1):1-8. doi:10.1097/PCC.0000000000001368.

Hill G, Ghanayem N, Hraska V, Jacobsen R, Mitchell M, Woods R, Ginde S. (2018). Variation in the
use of Fontan fenestration in the current surgical era. Progress in Pediatric Cardiology.
10.1016/j.ppedcard.2018.08.007.

Balkin E, Steurer M, Delagnes E, et al. Multicenter Mortality and Morbidity Associated with Pulmonary
Hypertension in the Pediatric Intensive Care Unit. Pulmonary Circulation. 2018.
doi:10.1177/2045893217745785. Epub 2017 Dec 18.

Balkin E, Zinter M, Rajagopal S, Keller R, Fineman J, Steurer M. Intensive Care Mortality Prognostic
Model for Pediatric Pulmonary Hypertension. Pediatr Crit Care Med. 2018 June 19. [Epub ahead of
print]

Gupta P, Rettiganti M, Gosset J, Daufeldt J, Rice T, Wetzel R. Development and Validation of an
Empiric Tool to Predict Favorable Neurologic Outcomes Among PICU Patients. Critical Care Medicine.
2018;46(1):108-115. doi:0.1097/CCM.0000000000002753. [Epub ahead of print 2017 Oct 6]

Reiter PD, Roth J, Wathen B, Lavelle J, Ridall LA. Low-Dose Epinephrine Boluses for Acute
Hypotension in the PICU*. Pediatric Critical Care Medicine. 2018;19(4):281-286.
doi:10.1097/pcc.0000000000001448.

Kolovos N, Gill J, Michelson P, Doctor A, Hartman M. Reduction in Mortality Following Pediatric Rapid
Response Team Implementation. Pediatric Critical Care Medicine. 2018: 19. (1).
10.1097/PCC.0000000000001519.

2017

Edwards J, Boscardin W, Lucas A, Dudley R. Repeated critical illness and unplanned readmissions
within 1 year to PICUs. Critical Care Medicine. 2017;45(8):1276-1284.

Flynn-O’Brien K, Fallat M, Rivera F, et al. Pediatric Trauma Assessment and Management Database:
Leveraging Existing Data Systems to Predict Mortality and Functional Status after Pediatric Injury.
Journal of The American College Of Surgeons. 2017;224:933-944.

Geneslaw A, Jia J, Lucas R, Agus M. Pediatric intermediate care and pediatric intensive care units:
PICU Metrics and an Analysis of Patients that use both. Journal of Critical Care. 2017;41:268-274.
doi:DOI:

Ortmann L, Manimtim W, Lachica C. Outcomes of Tracheostomy in Children Requiring Surgery for
Congenital Heart Disease. Pediatric Cardiology. 2017;38(2):296-301. doi:10.1007/s00246-016-1512-6.
Original Article First Online: 21 November 2016

McCrory M, Spaeder M, Gower E, Nakagawa T, et al. Time of Admission to the PICU and Mortality.
Pediatric Critical Care Medicine. 2017;18(10):915-923. doi:10.1097/PCC.0000000000001268 Feature
Article.

Patel M, Travers C, Stockwell J, Geller R, Kamat P, Grunwell J. Analysis of Interventions Required in
12,021 Children with Acute Intoxications Admitted to PICUs. Pediatric Critical Care Medicine.
2017;18(7):e281-e289. doi:10.1097/PCC.0000000000001187.

Russell R, Rettiganti M, Brundage N, Jeffries H, Gupta P. Performance of Pediatric Risk of Mortality
Score Among Critically Ill Children with Heart Disease. World Journal for Pediatric and Congenital Heart
Surgery . 2017;8(4):427-434. doi:10.1177/2150135117704656.

Doctor A, Zimmerman J, Agus M, et al. Pediatric Multiple Organ Dysfunction Syndrome: Promising
Therapies. Pediatric Critical Care Medicine. 2017;18(3):S67-S82.
doi:10.1097/pcc.0000000000001053.

Shein S, Slain K, Clayton J, McKee B, Rotta A, Wilson-Costello D. Neurologic and Functional Morbidity
in Critically Ill Children with Bronchiolitis*. Pediatric Critical Care Medicine. 2017;18(12):1106-1113.doi: 10.1097/pcc.0000000000001337.

Edwards J, Lucas A, Boscardin W, Dudley R. Repeated Critical Illness and Unplanned Readmissions
Within 1 Year to PICUs*. Critical Care Medicine. 2017;45(8):1276-1284.
doi:10.1097/ccm.0000000000002439.

Leroue M, Good R, Skillman H, Czaja A. Enteral Nutrition Practices in Critically Ill Children Requiring
Noninvasive Positive Pressure Ventilation*. Pediatric Critical Care Medicine. 2017;18(12):1093-1098.
doi:10.1097/pcc.0000000000001302.

2016

Edwards JD, Houtrow AJ, Lucas AR, et al. Children and young adults who received tracheostomies or
were initiated on long-term ventilation in pediatric ICUs. Pediatric Critical Care Medicine.
2016;17(8):e324-334.

Gall C, Wetzel R, Kolker A, Kanter R. Pediatric Triage in a Severe Pandemic: Maximizing Survival by
Establishing Triage Thresholds. Critical Care Medicine. 2016;44(9):1762-1768.
doi:10.1097/CCM.0000000000001759.

Flynn-O’Brien K, Fallat M, Rice T, Rivera R. Improving Risk-Adjusted Mortality Modeling in Pediatric
Trauma with a Novel Dataset. Pediatrics. 2016;137:270A. doi:10.1542/peds.137.Supplement_3.270A .

Coro M, Spaeder M, Penk J, Levin A, Futterman C. Unscheduled Pediatric Intensive Care Unit
Admissions in Patients with Cardiovascular Disease, Clinical Features and Outcomes. World Journal
for Pediatric and Congenital Heart Surgery. 2016; 7(4): 454-459. doi: 10.1177/2150135116648308.

Meyer M, Mikhailov T, Kuhn E, Collins M, Scanlon M. Pediatric Specialty Transport Teams are not
Associated with Decreased 48-Hour Pediatric Intensive Care Unit Mortality: A Propensity Analysis of
the VPS, LLC Database. Air Medical Journal. 2016;35(2): 73-78. doi:

Field-Ridley A, Dharmar M, Steinhorn D, McDonald C, Marcin J. ICU-Acquired Weakness is
Associated with Differences in Clinical Outcomes in Critically Ill Children. Pediatr Crit Care Med.
2016;17(1):53-7. doi: 10.1097/PCC.0000000000000538.

Gupta P, Rettiganti M, Rice T, Wetzel R. Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes
in Pediatric Intensive Care: A Multi-Center Study. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead
of print]. doi:10.1164/rccm.201512-2456OC.

McCrory M, Lee K, Scanlon M, Wakeham M. Predictors of need for mechanical ventilation at discharge
after Tracheostomy in the PICU. Pediatric Pulmonology. 2016;51(1):53-59. doi:10.1002/ppul.23195.
Epub 2015 Mar 30.

Heneghan J, Lansell A, Domowicz D, Shein S. Intensive Care Unit Readmissions Among Children with
Tracheostomies Placed Following Cardiac Arrest. Pediatrics. 2016;137:258A-258A.
doi:10.1542/peds.137.Supplement_3.258A.

Edwards J, Houtrow A, Vasilevskis E, et al. Children and Young Adults who Receive Tracheostomies or
were Intubated on Long Term Ventilation in the Pediatric ICU. PCCM. 2016; 17(8): e324-34. doi:
10.1097/PCC.0000000000000844.

Gupta P, Rettiganti M, Gossett J, Yeh J. Risk factors for mechanical ventilation and reintubation after
Pediatric Heart Surgery. Journal Thoracic Cardiovascular Surgery. 2016;151(2):451-458.
doi:10.1016/j.jtcvs.2015.09.080. Epub 2015 Sep 28

Gupta P, Rettiganti M, Jeffries H, Rice T. Epidemiology of Reintubation Among Children Undergoing
Heart Operations of Varying Complexity. Critical Care Medicine. 2016;44(12):126.
doi:10.1097/01.ccm.0000508876.60312.35.

Gupta P, Rettiganti M, Jeffries H, et al. Association of 24/7 In-house ICU Attending Coverage with
Outcomes in Children Undergoing Heart Operations. Ann Thorac Surg. (Accepted for Publication, In
Press). Ann Thorac Surg. 2016 Jun 18. [Epub ahead of print]. doi:

Gupta P, Rettiganti M, Rice T, Wetzel R. Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes
in Pediatric Intensive Care. A Multicenter Study. American Journal of Respiratory and Critical Care
Medicine. 2016;194(12). doi:10.1164/rccm.201512-2456OC .

Gupta P, Rettiganti M, Jeffries H, et al. Risk Factors and Outcomes of In-Hospital Cardiac Arrest
Following Pediatric Heart Operations of Varying Complexity. Resuscitation. 2016 May 13;105:1-7.
[Epub ahead of print]. doi: 10.1016/j.resuscitation.2016.04.022.

Gupta P, Tang X, Rettiganti M, et al. Association of House Staff Training with Mortality in Children with
Critical Illness. Acta Paediatrica. 2016;105(2): e60–e66, doi: 10.1111/apa.13223.

Ross P, Newth C, Leung D, Wetzel R, Khemani R. Obesity and Mortality Risk in Critically Ill Children.
Pediatrics. 2016;137(3):e20152035. Epub 2016 Feb 16. doi: 10.1542/peds.2015-2035.

Gupta P, Richardson T, Hall M, et al. Effect of Inhaled Nitric Oxide on Outcomes in Children with Acute
Lung Injury: Propensity Matched Analysis from a Linked Database. Crit Care Med. 2016 May 9. [Epub
ahead of print]. doi: 10.1097/CCM.0000000000001837.

Gupta P, Rettiganti M, Fisher P, Chang A, Rice T, Wetzel R. Association of Freestanding Children’s
Hospitals with Outcomes in Children with Critical Illness. Crit Care Med. 2016 Aug 4. [Epub ahead of
print]. doi:10.1097/CCM.0000000000001961.

Markovitz B, Kukuyeva I, Soto-Campos G, Khemani R. PICU Volume and Outcome: A SeverityAdjusted Analysis. PCCM. 2016;17(6):483-9. doi: 10.1097/PCC.0000000000000697.

Gupta P, Tang X, Rettiganti M, et al. Association of House Staff Training with Mortality in Children with
Critical Illness. Acta Paediatrica. 2016;105(2): e60–e66, doi: 10.1111/apa.13223.

Gupta P, Rettiganti M, Fisher P, Chang A, Rice T, Wetzel R. Association of Freestanding Children’s
Hospitals with Outcomes in Children with Critical Illness. Crit Care Med. 2016 Aug 4. [Epub ahead of
print]. doi:10.1097/CCM.0000000000001961.

Coro M, Spaeder M, Penk J, Levin A, Futterman C. Unscheduled Pediatric Intensive Care Unit
Admissions in Patients with Cardiovascular Disease, Clinical Features and Outcomes. World Journal
for Pediatric and Congenital Heart Surgery. 2016; 7(4): 454-459. doi: 10.1177/2150135116648308.

Gupta P, Rettiganti M, Rice T, Wetzel R. Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes
in Pediatric Intensive Care: A Multi-Center Study. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead
of print]. doi:10.1164/rccm.201512-2456OC.

Gupta P, Rettiganti M, Jeffries H, et al. Association of 24/7 In-house ICU Attending Coverage with
Outcomes in Children Undergoing Heart Operations. Ann Thorac Surg. (Accepted for Publication, In
Press). Ann Thorac Surg. 2016 Jun 18. [Epub ahead of print].
doi:http://dx.doi.org/10.1016/j.athoracsur.2016.04.042.

Edwards J, Houtrow A, Vasilevskis E, et al. Children and Young Adults who receive tracheostomies or
were intubated on Long Term Ventilation in the Pediatric ICU. PCCM. 2016; 17(8): e324-34. doi:
10.1097/PCC.0000000000000844.

Gupta P, Rettiganti M, Jeffries H, et al. Risk Factors and Outcomes of In-Hospital Cardiac Arrest
Following Pediatric Heart Operations of Varying Complexity. Resuscitation. 2016 May 13;105:1-7.
[Epub ahead of print]. doi: 10.1016/j.resuscitation.2016.04.022.

Gupta P, Richardson T, Hall M, et al. Effect of Inhaled Nitric Oxide on Outcomes in Children with Acute
Lung Injury: Propensity Matched Analysis from a Linked Database. Crit Care Med. 2016 May 9. [Epub
ahead of print]. doi: 10.1097/CCM.0000000000001837.

Markovitz B, Kukuyeva I, Soto-Campos G, Khemani R. PICU Volume and Outcome: A SeverityAdjusted Analysis. PCCM. 2016;17(6):483-9. doi: 10.1097/PCC.0000000000000697.

Meyer M, Mikhailov T, Kuhn E, Collins M, Scanlon M. Pediatric Specialty Transport Teams are not
Associated with Decreased 48-Hour Pediatric Intensive Care Unit Mortality: A Propensity Analysis of
the VPS, LLC Database. Air Medical Journal. 2016;35(2): 73-78.
doi: http://dx.doi.org/10.1016/j.amj.2015.12.003.

Ross P, Newth C, Leung D, Wetzel R, Khemani R. Obesity and Mortality Risk in Critically Ill
Children. Pediatrics. 2016;137(3):e20152035. Epub 2016 Feb 16. doi: 10.1542/peds.2015-2035.

Gupta P, Tang X, Rettiganti M, et al. Association of House Staff Training with Mortality in Children with
Critical Illness. Acta Paediatrica. 2016;105(2): e60–e66, doi: 10.1111/apa.13223.

Gupta P, Rettiganti M, Gossett J, et al. Risk factors for Mechanical Ventilation and Reintubation After
Pediatric Heart Surgery. The Journal of Thoracic and Cardiovascular Surgery. 2016;151(2):451 –
458.e3 doi: http://dx.doi.org/10.1016/j.jtcvs.2015.09.080.

Field-Ridley A, Dharmar M, Steinhorn D, McDonald C, Marcin J. ICU-Acquired Weakness is
Associated with Differences in Clinical Outcomes in Critically Ill Children. Pediatr Crit Care
Med. 2016;17(1):53-7. doi: 10.1097/PCC.0000000000000538.

2015

Jeffries H, Soto-Campos G, Katch A, Gall C, Rice T, Wetzel R. A Pediatric Index of Cardiac Surgical
Intensive Care Mortality Risk Score for Pediatric Cardiac Critical Care. Pediatr Crit Care
Med. 2015;16(9):846–852. doi: 10.1097/PCC.0000000000000489.

Nguyen T, Bhalla A, Leung D, Khemani R, Ross P. PICU Mortality and Body Habitus in Patients with
Septicemia or Septic Shock. Critical Care Medicine.2015;43(12):253–254. doi:
10.1097/01.ccm.0000474839.78529.93

Zinter M, Dvorak C, Spicer A, Cowan M, Sapru A. New Insights into Multicenter PICU Mortality Among
Pediatric Hematopoietic Stem Cell Transplant Patients. Crit Care Med. 2015;43(9):1986-94. doi:
10.1097/CCM.0000000000001085.

Toltzis P, Soto-Campus G, Kuhn E, Hahn R, Kanter R, Wetzel R. Evidence-Based Pediatric Outcome
Predictors to Guide the Allocation of Critical Care Resources in a Mass Casualty Event. Pediatr Crit
Care Med. 2015;16(7):e207–e216. doi: 10.1097/PCC.0000000000000481

Gupta P, Tang X, Gossett J, et al. Variation of Ventilation
Practices with center volume after pediatric heart surgery. Clin Cardiol. 2015 Mar;38(3):178-84. doi:
10.1002/clc.22374. Epub 2015 Feb 23.

2014

Edwards J, Vasilevskis E, Yoo E, et al. Adults with childhood-onset chronic conditions admitted to US
pediatric and adult intensive care units. J Crit Care. 2015 Feb;30(1):201-6. doi:
10.1016/j.jcrc.2014.10.016. Epub 2014 Oct 25.

McCrory M, Gower E, Simpson S, Nakagawa T, Mou S, Morris P. Off-Hours Admission to Pediatric
Intensive Care and Mortality.Pediatrics. Pediatrics. 2014 Nov;134(5):e1345-53. doi:
10.1542/peds.2014-1071. Epub 2014 Oct 6.

Panchal AK, Manzi J, Connolly S, Christensen M, Wakeham M, Goday PS, Mikhailov
TA. Safety of Enteral Feedings in Critically Ill Children Receiving Vasoactive Agents. JPEN J
Parenter Enteral Nutr. 2014 Aug 28. pii: 0148607114546533.

Gupta P, Tang X, Gall C, et al. Epidemiology and outcomes of in-hospital cardiac arrest in critically ill
children across hospitals of varied center volume: a multi-center analysis. Resuscitation. 2014
Nov;85(11):1473-9. doi: 10.1016/j.resuscitation.2014.07.016. Epub 2014 Aug 7.

Zinter M, DuBois S, Spicer A, et al. Pediatric cancer type predicts infection rate, need for critical care
intervention, and mortality in the pediatric intensive care unit. Intensive Care Med. 2014
Oct;40(10):1536-44. doi: 10.1007/s00134-014-3389-2. Epub 2014 Jul 15.

Bone, M, Feinglass, J, Goodman, D. Risk Factors for Acquiring Functional and Cognitive Disabilities
During Admission to a PICU. Pediatr Crit Care Med. 2014 Sep;15(7):640-8. doi:
10.1097/PCC.0000000000000199

Panchal A, Manzi J, Connolly S, et al., Safety of Enteral Feedings in Critical Ill Children on Vasoactive
Agents. JPEN J Parenter Enteral Nutr. 2014 Aug 28. pii: 0148607114546533. [Epub ahead of print]

Gaies M, Jeffries H, Niebler R, et al. Vasoactive-Inotropic Score Is Associated with Outcome After
Infant Cardiac Surgery: An Analysis From the Pediatric Cardiac Critical Care Consortium and Virtual
PICU System Registries. PCCM 2014. 15 (6). pp529-537. DOI: 10.1097/PCC.0000000000000153

Gupta P, Tang X, Gossett J, et al. Association of center volume with outcomes in critically ill children
with acute asthma. Ann Allergy Asthma Immunol. 2014 Jul;113(1):42-7. doi:
10.1016/j.anai.2014.04.020. Epub 2014 May 14.

Wakeham M, Kuhn E, Lee J, McCrory M, Scanlon M, Use of Tracheostomy in the Pediatric Intensive
Care Unit among Patients Requiring Prolonged Mechanical Ventilation.Intensive Care Med 2014
Jun;40(6)863-70.doi: 10.1007/s00134-014-3298-4. Epub 2014 May 1.

Mikhailov, T, Kuhn, E, Manzi,, J, et al. Early enteral nutrition is associated with lower mortality in
critically ill children. JPEN J Parenter Enteral Nutr. 2014 May;38(4):459-66. doi:
10.1177/0148607113517903. Epub 2014 Jan 8.

Gupta P, Kacmarek RM, Wetzel RC. It is Too Eartly to declare Early or Late Rescue High-Frequency
Oscillatory Ventilation Dead- Reply. JAMA Pediatr. 2014; 168(9): 863. doi:

Gupta P, Green J, Tang X, et al. Comparison of high-frequency oscillatory ventilation and conventional
mechanical ventilation in pediatric respiratory failure. JAMA Pediatr. 2014 Mar;168(3):243-9, doi:
10.1001/jamapediatrics.2013.4463.

Iannucci G, Oster M, Chanani N, et al. The Relationship between In-House Attending Coverage and
Duration of Mechanical Ventilation Following Congenital Heart Surgery, Pediatr Crit Care Med. 2014
Mar;15(3):258-63. doi: 10.1097/PCC.0000000000000068.

Russell, R, Ghanayem, N, Kuhn, E, Jeffries, H, Scanlon, M, & Rice, T. Relationship between riskadjustment. World Journal for Pediatric and Congenital Heart Surgery, World J Pediatr Congenit Heart
Surg. 2014 Jan 1;5(1):16-21. doi: 10.1177/2150135113510008.

2013

Edwards J, Lucas A, Stone P, Boscardin W, Dudley R, Frequency, Risk Factors, and Outcomes of
Early Unplanned Readmissions to PICUs. Crit Care Med. 2013 Dec;41(12):2773-83. doi:
10.1097/CCM.0b013e31829eb970.

Wakeham M, Christensen M, Manzi J, Kuhn EM, Scanlon M, Goday PS, Mikhailov
TA. Registered dietitians making a difference: early medical record documentation of estimated energy
requirement in critically ill children is associated with higher daily energy intake and with use of
the enteral route. J Acad Nutr Diet. 2013 Oct;113(10):1311-6. doi: 10.1016/j.jand.2013.04.025. Epub
2013 Jun 28.

Ghuman, A, Newth, C, Khemani, R. Impact of Gender on Sepsis Mortality and Severity of Illness for
Prepubertal and Postpubertal Children. The Journal of Pediatrics Sept 2013.163(3),pgs 835-840.e1

Czaja, A, Hosokawa, P, & Henderson, W. Unscheduled readmissions to the picu: epidemiology, risk
factors, and variation among centers. Pediatr Crit Care Med., 2013 Jul;14(6):571-9. doi:
10.1097/PCC.0b013e3182917a68.

Cassidy, L, Lambropoulos, D, Enters, J, Farahzad, M, Gourlay, D, Lal, D, Health Disparities Analysis of
Critically Ill Pediatric Trauma Patients in Milwaukee, Wisconsin, J Am Coll Surg. 2013 Aug;217(2):233-
9. doi: 10.1016/j.jamcollsurg.2013.02.032. Epub 2013 May 8

Edwards J, Houtrow A, Vasilevskis E, Dudley R, Okumura M; A multi-institutional profile of adults
admitted to pediatric intensive care units, JAMA Pediatr. 2013 May;167(5):436-43. doi:
10.1001/jamapediatrics.2013.1316

Shibata, S, Khemani, R, Markovitz, B. Patient Origin Is Associated With Duration of Endotracheal
Intubation and PICU Length of Stay for Children With Status Asthmaticus. J Intensive Care Med. 2014
May-Jun;29(3):154-9. doi: 10.1177/0885066613476446. Epub 2013 Feb 11

2012

Sala, K, Karamessinis L, Zucker A, Carroll C. Respiratory Failure in Children with Status Asthmaticus: A Review of the VPS Database. Pediatric Allergy, Immunology, and Pulmonology. December 2012, 25(4):
226-230. doi:10.1089/ped.2012.0188.

Edwards J, Houtrow (A, Vasilevskis E, et al, Chronic conditions among children admitted to U.S.
pediatric intensive care units: their prevalence and impact on risk for mortality and prolonged length of
stay. Crit Care Med. 2012 Jul;40(7):2196-203.

Weiss, S, Parker, B, Bullock, M, et al, Defining pediatric sepsis by different criteria: Discrepancies in
populations and implications for clinical practice, Pediatr Crit Care Med. 2012 Jul;13(4):e219-26. doi:
10.1097/PCC.0b013e31823c98da.

Ingaramo, O., Khemani, R., Markovitz, B, Epstein, D, Effect of race on the timing of the Glenn and
Fontan procedures for single-ventricle congenital heart disease, Pediatr Crit Care Med. 2012
Mar;13(2):174-7. doi: 10.1097/PCC.0b013e3182231862.

2011

Higgerson, R, Laswon, K, Christie, L, et al, Incidence and Risk Factors Associated with Venous
Thrombotic Events in Pediatric ICU Patients. Pediatr Crit Care Med. 2011 Nov;12(6):628-34.
doi:10.1097/PCC.0b013e318207124a

Hanson, S, Lawson, K, Brown A, et al, Current Treatment of Venous Thromboembolism in Children
Admitted to Pediatric Intensive Care Units. Paediatr Anaesth. 2011 Oct;21(10):1052-7. doi:
10.1111/j.1460-9592.2011.03653.x. Epub 2011 Jul 18

Wetzel, R, Sachdeva, R, Rice, T, Are all ICUs the same?. Paediatr Anaesth. 2011 Jul;21(7):787-93.
doi: 10.1111/j.1460-9592.2011.03595.x. Epub 2011 May 9

Faustino, E, Lawson, K, Northrup V, Higgerson R, Mortality-adjusted Duration of Mechanical Ventilation
in Critically Ill Children with Symptomatic Central Venous Line-Related Deep Venous Thrombosis. Crit
Care Med. 2011 May;39(5):1151-6. doi: 10.1097/CCM.0b013e31820eb8a1

Deeter K, King M, Ridling D, Irby G, Lynn A, Zimmerman J. Successful Implementation of a Pediatric
Sedation Protocol For Mechanically Ventilated Patients. Crit Care Med. 2011 Apr;39(4):683-8. doi:
10.1097/CCM.0b013e318206cebf

Epstein D, Wong C, Khemani R, et al. Race/Ethnicity is not associated with mortality in the PICU.
Pediatrics. Pediatrics: 2011 Mar;127(3):e588-97. Doi: 10.1542/peds. 2010-0394 Epub 2011 Feb 28.

Schindler C, Mikhailov T, Kuhn E, et al . Protecting Fragile Skin: Nursing Interventions to Decrease
Development of Pressure Ulcers in Pediatric Intensive Care. Am J Crit Care. 2011 Jan;20(1):26-35.

24/7 PICU attending coverage not associated with improved outcomes Crit Care Med. 2012 Feb: 40(2)
Czaja, A, Scanlon, M, Kuhn, E, & Jeffries, H. Performance of the pediatric index of mortality 2
for pediatric cardiac surgery patients. Pediatr Crit Care Med, 2011; 12(2), 184-9. doi:
10.1097/PCC.0b013e3181e89694

2010

Lee K, Tieves K, Scanlon M. Alterations in end-of-life support in the pediatric intensive care unit.
Pediatrics. 2010 Oct; 126(4):e859-64. Epub 2010 Sep 6. Doi: 101542/pedS2010-2014.

Does in-house attending coverage in PICU setting impact patients come Outcomes? Crit Care Med 2010, Sept:39(9)

2009

Typpo K, Petersen N, Hallman D, Markovitz B, Mariscalco M, Day 1 multiple organ dysfunction
syndrome is associated with poor functional outcome and mortality in the pediatric intensive care unit,
Pediatr Crit Care Med. 2009 Sep;10(5):562-70.

Gorman M, Sachdeva R, Rice T, Wetzel R., Support for PICUs and the PRISM scoring algorithms,
Pediatr Crit Care Med. 2009 Jan;10(1):143-4. doi: 10.1097/PCC.0b013e3181937bf4

Markovitz B, Khemani R. Impact of PICU volume on severity of illness adjusted mortality. Critical Care
Medicine (supp) (2009) Dec;37(12) A356(729). http://journals.lww.com/ccmjournal/toc/2009/12001

Gall CM, Jeffries HE, Lee JY, Kuhn E, Wetzel RC, Rice TB, Gorman M, Sachdeva RC. Development of
a new method to risk adjust outcomes for cardiac critical care patients [abstract]. Crit Care Med.
2009;37(12 suppl):A291 http://journals.lww.com/ccmjournal/toc/2009/12001

Goday P, Vermilyea S, Kuhn E, Otto M, Mikhailov T. Admission anthropometric measures and
outcomes in the pediatric intensive care unit (PICU) [abstract]. Presented as a poster at Clinical
Nutrition Week 2009. JPEN J Parenter Enteral Nutr 33(2):237-8, 2009

Sachdeva R, Kuhn E, Gall C, Rice T, Gorman M, Wetzel R. A need for development of diagnosisspecific severity of illness tools for risk adjustment [abstract 338]. In: Critical Care Medicine, 2009;
36(suppl 12):A83. http://journals.lww.com/ccmjournal/toc/2009/12001

Wetzel R, Kuhn E, Gall C, Rice T, Sachdeva R, Gorman M. Demonstrating time-dependent drift in a
validated risk adjustment tool [abstract 27]. In: Critical Care Medicine, 2009; 36(suppl
12):A8. http://journals.lww.com/ccmjournal/toc/2009/12001

2008

LaRovere J, Jeffries H, Sachdeva R, et al, Databases for assessing the outcomes of the treatment of
patients with congenital and paediatric cardiac disease–the perspective of critical care, Cardiol Young.
2008 Dec;18 Suppl 2:130-6. Doi: 10.1017/S1047951108002886.

Odetola F, Rosenberg A, Davis M, Clark S, Dechert R, Shanley T., Do outcomes vary according to the
source of admission to the pediatric intensive care unit? Pediatr Crit Care Med. 2008 Jan;9(1):20-5.
Doi: 10.1097/01.PCC.0000298642.11872:29.

Goday P, Kuhn E, Sachdeva R Mikhailov T. Does admission weight influence mortality and morbidity in
the Pediatric Intensive Care Unit (PICU)? Oral presentation at Clinical Nutrition Week 2008. JPEN J
Parenter Enteral Nutr 32:316-7,
2008 https://www.abbott.ch/fileadmin/docs/nutrition/Newsletter_ASPEN_2008.pdf

2007

Schindler C, Mikhailov T, Fischer K, Lukasiewicz G, Kuhn E, Duncan L., Skin integrity in critically ill and
injured children. Am J Crit Care. 2007 Nov;16(6):568-74.

Odetola F, Clark S, Dechert R, Shanley T.,Going back for more: an evaluation of clinical outcomes and
characteristics of readmissions to a pediatric intensive care unit., Pediatr Crit Care Med. 2007
Jul;8(4):343-7; CEU quiz 357.

2006

Odetola F, Shanley T, Gurney J, et al. Characteristics and outcomes of interhospital transfers from level
II to level I pediatric intensive care units., Pediatr Crit Care Med. 2006 Nov;7(6):536-40.

Sachdeva RC, Rice TB, Implementation of a validated Pediatric Critical Care Database for Quality and
Outcomes Assessment., Pediatric Critical Care Medicine September 2006.

Sachdeva R, Wetzel R, Gorman M, Rice T. Public reporting of Outcomes, Medical Malpractice Trends
and Pediatric Intensive Care in the U.S. Pediatric Critical Care Medicine, September 2006, Volume 7
Issue 5: 515

Sachdeva R, Wetzel R, Gorman M, Rice T. Implementation of a validated pediatric critical care
database for quality and outcomes assessment. Pediatr Crit Care Med. 2006;7(5):515

Sachdeva R; Wetzel R; Gorman M; Rice, T. Public Reporting of Outcomes, Medical Malpractice
Trends, and Pediatric Intensive Care in the U.S. [abstract]. Pediatr Crit Care Med. 2006;7(5):515.

Sachdeva RC., Rice TB., Enhancing Transparency and Communication to Improve Quality. NACHRI
2006 Annual Meeting, Boston, MA, October 2006.

2005

Scanlon M, Wetzel R, Rice T. Application of pediatric critical care quality indicators using a picu clinical
database [abstract]. Pediatr Crit Care Med. 2005;6(1):A7.

Tieves K, Scanlon M, Rice T, Havens P. Outcome of pediatric patients with head injury: center
differences in mortality and functional outcome at picu discharge [abstract]. Pediatr Crit Care Med.
2005;6(1):A58.

Tieves, K, Scanlon, M, Rice, T, Havens, P, Outcome of Pediatric Patients with Head Injury: Center
differences in mortality and functional outcome at PICU Discharge. Pediatric Critical Care Colloquium,

Scanlon, M. C., Tieves, K. S., Wetzel, R., Rice, T. B. Application of Pediatric Critical Care Quality
Indicators to a PICU Clinical Database. Pediatric Critical Care Colloquium, New York, New York,
September 2004. Pediatric Critical Care Medicine 2005; 6 (1) p. 104.New York, New York, September 2004. Pediatric Critical Care Medicine 2005; 6 (1) p.118.

Kane J, Tieves K, Scanlon M, Klem S, Rice T. Admission Time and Mortality in Patients Admitted to
the Pediatric Intensive Care Unit [abstract]. Poster Presentation Society of Critical Care Medicine 34th
Critical Care Conference, Phoenix, AZ. USA. Jan 115-19, 2005. Poster Presentation:
Epdemiology/Outcomes Pediatrics 1. Crit Care Med 2004; 32(12) Supplement: A85.

2003

Kurachek S, Newth C, Quasney M, et al. Extubation failure in pediatric intensive care: a multiple-centerstudy of risk factors and outcomes., Crit Care Med. 2003 Nov;31(11):2657-64.